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CLARITY increases sensitivity and specificity of fluorescence immunostaining in long-term archived human brain tissue

BACKGROUND: Post mortem human brain tissue is an essential resource to study cell types, connectivity as well as subcellular structures down to the molecular setup of the central nervous system especially with respect to the plethora of brain diseases. A key method is immunostaining with fluorescent...

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Detalles Bibliográficos
Autores principales: Woelfle, Sarah, Deshpande, Dhruva, Feldengut, Simone, Braak, Heiko, Del Tredici, Kelly, Roselli, Francesco, Deisseroth, Karl, Michaelis, Jens, Boeckers, Tobias M., Schön, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207789/
https://www.ncbi.nlm.nih.gov/pubmed/37221592
http://dx.doi.org/10.1186/s12915-023-01582-6

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