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CLARITY increases sensitivity and specificity of fluorescence immunostaining in long-term archived human brain tissue
BACKGROUND: Post mortem human brain tissue is an essential resource to study cell types, connectivity as well as subcellular structures down to the molecular setup of the central nervous system especially with respect to the plethora of brain diseases. A key method is immunostaining with fluorescent...
Autores principales: | Woelfle, Sarah, Deshpande, Dhruva, Feldengut, Simone, Braak, Heiko, Del Tredici, Kelly, Roselli, Francesco, Deisseroth, Karl, Michaelis, Jens, Boeckers, Tobias M., Schön, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207789/ https://www.ncbi.nlm.nih.gov/pubmed/37221592 http://dx.doi.org/10.1186/s12915-023-01582-6 |
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