Integration of multiomics data shows down regulation of mismatch repair and tubulin pathways in triple-negative chemotherapy-resistant breast tumors

BACKGROUND: Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype. Patients with TNBC are primarily treated with neoadjuvant chemotherapy (NAC). The response to NAC is prognostic, with reductions in overall survival and disease-free survival rates in those patients who do...

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Detalles Bibliográficos
Autores principales: Tang, Xiaojia, Thompson, Kevin J., Kalari, Krishna R., Sinnwell, Jason P., Suman, Vera J., Vedell, Peter T., McLaughlin, Sarah A., Northfelt, Donald W., Aspitia, Alvaro Moreno, Gray, Richard J., Carter, Jodi M., Weinshilboum, Richard, Wang, Liewei, Boughey, Judy C., Goetz, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207800/
https://www.ncbi.nlm.nih.gov/pubmed/37226243
http://dx.doi.org/10.1186/s13058-023-01656-x

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