Drug mechanism enrichment analysis improves prioritization of therapeutics for repurposing

BACKGROUND: There is a pressing need for improved methods to identify effective therapeutics for diseases. Many computational approaches have been developed to repurpose existing drugs to meet this need. However, these tools often output long lists of candidate drugs that are difficult to interpret,...

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Detalles Bibliográficos
Autores principales: Garana, Belinda B., Joly, James H., Delfarah, Alireza, Hong, Hyunjun, Graham, Nicholas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207828/
https://www.ncbi.nlm.nih.gov/pubmed/37226094
http://dx.doi.org/10.1186/s12859-023-05343-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207828/
https://www.ncbi.nlm.nih.gov/pubmed/37226094
http://dx.doi.org/10.1186/s12859-023-05343-8

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