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Drug mechanism enrichment analysis improves prioritization of therapeutics for repurposing
BACKGROUND: There is a pressing need for improved methods to identify effective therapeutics for diseases. Many computational approaches have been developed to repurpose existing drugs to meet this need. However, these tools often output long lists of candidate drugs that are difficult to interpret,...
Autores principales: | Garana, Belinda B., Joly, James H., Delfarah, Alireza, Hong, Hyunjun, Graham, Nicholas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207828/ https://www.ncbi.nlm.nih.gov/pubmed/37226094 http://dx.doi.org/10.1186/s12859-023-05343-8 |
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