Cargando…

Identifying the neurodevelopmental and psychiatric signatures of genomic disorders associated with intellectual disability: a machine learning approach

BACKGROUND: Genomic conditions can be associated with developmental delay, intellectual disability, autism spectrum disorder, and physical and mental health symptoms. They are individually rare and highly variable in presentation, which limits the use of standard clinical guidelines for diagnosis an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Donnelly, Nicholas, Cunningham, Adam, Salas, Sergio Marco, Bracher-Smith, Matthew, Chawner, Samuel, Stochl, Jan, Ford, Tamsin, Raymond, F. Lucy, Escott-Price, Valentina, van den Bree, Marianne B. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207854/ https://www.ncbi.nlm.nih.gov/pubmed/37221545 http://dx.doi.org/10.1186/s13229-023-00549-2

Ejemplares similares

Neuropsychiatric risk in children with intellectual disability of genetic origin: IMAGINE, a UK national cohort study
por: Wolstencroft, Jeanne, et al.
Publicado: (2022)

Sleep disturbance as a transdiagnostic marker of psychiatric risk in children with neurodevelopmental risk genetic conditions
por: Chawner, Samuel J. R. A., et al.
Publicado: (2023)

Neurodevelopmental risk copy number variants in adults with intellectual disabilities and comorbid psychiatric disorders
por: Thygesen, Johan H., et al.
Publicado: (2018)

Mental health impact of autism on families of children with intellectual and developmental disabilities of genetic origin
por: Wolstencroft, Jeanne, et al.
Publicado: (2023)

Role of nucleosome remodeling in neurodevelopmental and intellectual disability disorders
por: López, Alberto J., et al.
Publicado: (2015)

NRSF/REST lies at the intersection between epigenetic regulation, miRNA-mediated gene control and neurodevelopmental pathways associated with Intellectual disability (ID) and Schizophrenia
por: Alsaqati, Mouhamed, et al.
Publicado: (2022)

The Psychiatric Risk Gene Transcription Factor 4 (TCF4) Regulates Neurodevelopmental Pathways Associated With Schizophrenia, Autism, and Intellectual Disability
por: Forrest, Marc P, et al.
Publicado: (2018)

Psychiatric practice for intellectual disability in the USA: challenges and advances
por: Ruedrich, Stephen
Publicado: (2009)

Emphasizing the Health Benefits of Vitamin D for Those with Neurodevelopmental Disorders and Intellectual Disabilities
por: Grant, William B., et al.
Publicado: (2015)

Improving Psychiatric Hospital Care for Pediatric Patients with Autism Spectrum Disorders and Intellectual Disabilities
por: Gabriels, Robin L., et al.
Publicado: (2012)

Prevalence of psychiatric morbidity among parents of children with intellectual disability
por: Tak, Nandkisor K., et al.
Publicado: (2018)

Differences of Psychopathology of Psychiatric Disorders in Adult Patients with Intellectual Disability
por: Musalek, M.
Publicado: (2022)

Investigating mechanisms underlying neurodevelopmental phenotypes of autistic and intellectual disability disorders: a perspective
por: Kroon, Tim, et al.
Publicado: (2013)

The role of glia in epilepsy, intellectual disability, and other neurodevelopmental disorders in tuberous sclerosis complex
por: Wong, Michael
Publicado: (2019)

Monoallelic and bi-allelic variants in NCDN cause neurodevelopmental delay, intellectual disability, and epilepsy
por: Fatima, Ambrin, et al.
Publicado: (2021)

Monoallelic and bi-allelic variants in NCDN cause neurodevelopmental delay, intellectual disability, and epilepsy
por: Fatima, Ambrin, et al.
Publicado: (2022)

The Emerging Roles of Long Non-Coding RNAs in Intellectual Disability and Related Neurodevelopmental Disorders
por: Liaci, Carla, et al.
Publicado: (2022)

Neurodevelopmental Trajectories and Psychiatric Morbidity: Lessons Learned From the 22q11.2 Deletion Syndrome
por: Fiksinski, Ania M., et al.
Publicado: (2021)

Assessment of emotions and behaviour by the Developmental Behaviour Checklist in young people with neurodevelopmental CNVs
por: Cunningham, Adam C., et al.
Publicado: (2022)

TAF1, associated with intellectual disability in humans, is essential for embryogenesis and regulates neurodevelopmental processes in zebrafish
por: Gudmundsson, Sanna, et al.
Publicado: (2019)

Novel variants underlying autosomal recessive neurodevelopmental disorders with intellectual disability in Iranian consanguineous families
por: Moudi, Mahdiyeh, et al.
Publicado: (2022)

Understanding the Implications of Peer Support for Families of Children With Neurodevelopmental and Intellectual Disabilities: A Scoping Review
por: Chakraborti, Michelle, et al.
Publicado: (2021)

PTCHD1: Identification and Neurodevelopmental Contributions of an Autism Spectrum Disorder and Intellectual Disability Susceptibility Gene
por: Pastore, Stephen F., et al.
Publicado: (2022)

Shared Neurodevelopmental Perturbations Can Lead to Intellectual Disability in Individuals with Distinct Rare Chromosome Duplications
por: Corrêa, Thiago, et al.
Publicado: (2021)

Missense and truncating variants in CHD5 in a dominant neurodevelopmental disorder with intellectual disability, behavioral disturbances, and epilepsy
por: Parenti, Ilaria, et al.
Publicado: (2021)

KCNK18 Biallelic Variants Associated with Intellectual Disability and Neurodevelopmental Disorders Alter TRESK Channel Activity
por: Pavinato, Lisa, et al.
Publicado: (2021)

Psychiatric disorders in adolescents and young adults with Down syndrome and other intellectual disabilities
por: Dykens, Elisabeth M, et al.
Publicado: (2015)

Chromosomal microarray testing in adults with intellectual disability presenting with comorbid psychiatric disorders
por: Wolfe, Kate, et al.
Publicado: (2017)

A ‘forgettable minority’? Psychiatric Institutions and the Intellectually Disabled in Ireland, 1965–84
por: Kilgannon, David
Publicado: (2020)

Autism: A model of neurodevelopmental diversity informed by genomics
por: Chawner, Samuel J. R. A., et al.
Publicado: (2022)

Inaugural annual special section of the intellectual and developmental disabilities research centers: developmental cognitive neuroscience and neurodevelopmental disorders
por: Jeste, Shafali Spurling, et al.
Publicado: (2018)

Neurodevelopmental Syndrome with Intellectual Disability, Speech Impairment, and Quadrupedia Is Associated with Glutamate Receptor Delta 2 Gene Defect
por: Grigorenko, Anastasia P., et al.
Publicado: (2022)

Association of maternal diabetes with neurodevelopmental disorders: autism spectrum disorders, attention-deficit/hyperactivity disorder and intellectual disability
por: Chen, Shuyun, et al.
Publicado: (2020)

Third-Generation Behavioural Therapies in the Context of Neurodevelopmental Problems and Intellectual Disabilities: A Randomised Clinical Trial with Parents
por: Lobato, David, et al.
Publicado: (2023)

Neurodevelopmental dimensional assessment of young children at high genomic risk of neuropsychiatric conditions
por: Chawner, Samuel J. R. A., et al.
Publicado: (2023)

Antipsychotic Use With and Without Comorbid Psychiatric Diagnosis Among Adults with Intellectual and Developmental Disabilities
por: Lunsky, Yona, et al.
Publicado: (2017)

Gender differences in psychiatric diagnoses in older people with intellectual disability: a register study
por: Axmon, Anna, et al.
Publicado: (2017)

The episodic buffer in children with intellectual disabilities: An exploratory study
por: Henry, Lucy A.
Publicado: (2010)

Setting priorities for people with intellectual disability/intellectual developmental disorders across the lifespan: a call to action by the World Psychiatric Association
por: Roy, Ashok, et al.
Publicado: (2021)

Behavioural, psychiatric and psychosocial factors associated with aggressive behaviour in adults with intellectual disabilities: A systematic review and narrative analysis
por: van den Akker, Natalie, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_rtpp4di5momp55m6blmj4btkps