Cargando…

Evaluation of Type 2 Diabetes Risk Variants (Alleles) in the Pashtun Ethnic Population of Pakistan

OBJECTIVE: To evaluate the Type 2 Diabetes (T2D) risk variants in the Pashtun ethnic population of Khyber Pakhtunkhwa using nascent whole-exome sequencing (WES) to better understand the pathogenesis of this complex polygenic disorder. METHODOLOGY: A total of 100 confirmed patients with T2D of Pashtu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jan, Asif, Saeed, Muhammad, Zakiullah, Akbar, Rani, Khan, Hamayun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Journal of the ASEAN Federation of Endocrine Societies 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207872/ https://www.ncbi.nlm.nih.gov/pubmed/37234924 http://dx.doi.org/10.15605/jafes.037.S3

Ejemplares similares

Association of HLA-B Gene Polymorphisms with Type 2 Diabetes in Pashtun Ethnic Population of Khyber Pakhtunkhwa, Pakistan
por: Jan, Asif, et al.
Publicado: (2021)

Association between Aldosterone Synthase (CYP11B2) Gene Polymorphism and Hypertension in Pashtun Ethnic Population of Khyber Pakhtunkwha, Pakistan
por: Shah, Waheed Ali, et al.
Publicado: (2023)

Validation of Genome-Wide Association Studies (GWAS)-Identified Type 2 Diabetes Mellitus Risk Variants in Pakistani Pashtun Population
por: Jan, Asif, et al.
Publicado: (2022)

Decoding type 2 diabetes mellitus genetic risk variants in Pakistani Pashtun ethnic population using the nascent whole exome sequencing and MassARRAY genotyping: A case-control association study
por: Jan, Asif, et al.
Publicado: (2023)

Association of APOE (rs429358 and rs7412) and PON1 (Q192R and L55M) Variants with Myocardial Infarction in the Pashtun Ethnic Population of Khyber Pakhtunkhwa, Pakistan
por: Rahman, Naveed, et al.
Publicado: (2023)

Association of CYP2C9*2 Allele with Sulphonylurea-Induced Hypoglycaemia in Type 2 Diabetes Mellitus Patients: A Pharmacogenetic Study in Pakistani Pashtun Population
por: Jan, Asif, et al.
Publicado: (2023)

Association of ATM, CDH1 and TP53 genes polymorphisms with familial breast cancer in patients of Khyber Pakhtunkhwa, Pakistan
por: Rahim, Abdur, et al.
Publicado: (2022)

Risk association of RANKL and OPG gene polymorphism with breast cancer to bone metastasis in Pashtun population of Khyber Pakhtunkhwa, Pakistan
por: Hayat, Faiza, et al.
Publicado: (2022)

Analysis of Skin Pigmentation and Genetic Ancestry in Three Subpopulations from Pakistan: Punjabi, Pashtun, and Baloch
por: Shan, Muhammad Adnan, et al.
Publicado: (2021)

Ethnogynaecological Assessment of Medicinal Plants in Pashtun's Tribal Society
por: Adnan, Muhammad, et al.
Publicado: (2015)

Mutation in Phospholipase C, δ1 (PLCD1) Gene Underlies Hereditary Leukonychia in a Pashtun Family and Review of The Literature
por: Khan, AK, et al.
Publicado: (2018)

Risk of Atherosclerotic Cardiovascular Diseases in various Ethnicities of Pakistan
por: Ashraf, Tariq, et al.
Publicado: (2020)

Prevalence of Type II diabetes in District Dir Lower in Pakistan
por: Akhtar, Sohail, et al.
Publicado: (2016)

Frequency of Gastroparesis Symptoms in Patients With Type-2 Diabetes Mellitus at a Tertiary Care Hospital in Pakistan
por: Asif, Mohammad Shahzad, et al.
Publicado: (2023)

Common Cancers in Karachi, Pakistan: 2010-2019 Cancer Data from the Dow Cancer Registry
por: Qureshi, Muhammad Asif, et al.
Publicado: (2020)

Genetic diversity and forensic application of Y-filer STRs in four major ethnic groups of Pakistan
por: Ikram, Muhammad Salman, et al.
Publicado: (2022)

Gender-based adjustment problems of divorcees in Hazara Division, Pakistan
por: Rubab, Kanwal, et al.
Publicado: (2023)

Spatio-temporal variations in wheat aphid populations and their natural enemies in four agro-ecological zones of Pakistan
por: Faheem, Muhammad, et al.
Publicado: (2019)

Subgenomic sequence analysis reveals emergence of new circulating recombinant forms of HIV-1 in Pakistan
por: Zahid, Maria, et al.
Publicado: (2022)

Variations in the frequencies of polymorphisms in the CYP2C9 gene in six major ethnicities of Pakistan
por: Ahmed, Sagheer, et al.
Publicado: (2020)

Ethnobotanical and antibacterial study of Primula plants traditionally used in the indigenous communities of Western Himalaya, Pakistan
por: Khan, Saima, et al.
Publicado: (2022)

Genomic variants identified from whole-genome resequencing of indicine cattle breeds from Pakistan
por: Iqbal, Naveed, et al.
Publicado: (2019)

Patterns of livestock depredation and Human–wildlife conflict in Misgar valley of Hunza, Pakistan
por: Bano, Rubina, et al.
Publicado: (2021)

Type 2 Diabetes Risk Allele Loci in the Qatari Population
por: O’Beirne, Sarah L., et al.
Publicado: (2016)

A randomized control trial of primary care-based management of type 2 diabetes by a pharmacist in Pakistan
por: Javaid, Zaida, et al.
Publicado: (2019)

First report regarding molecular epidemiology and novel variant identification of Anaplasma centrale in cattle from Pakistan
por: Ashraf, Sehrish, et al.
Publicado: (2021)

Insect pollinator diversity in four forested ecosystems of southern Punjab, Pakistan
por: Bashir, Muhammad Amjad, et al.
Publicado: (2019)

Epidemiology and clinical findings associated with enteroviral acute flaccid paralysis in Pakistan
por: Saeed, Mohsan, et al.
Publicado: (2007)

Fasting Glucagon Level in Type 2 Diabetes and Impaired Glucose Tolerance and Its Association With Diabetes-Associated Clinical Parameters: A Study From Karachi, Pakistan
por: Abbas, Eraj, et al.
Publicado: (2021)

Genotyping of HCV RNA Reveals That 3a Is the Most Prevalent Genotype in Mardan, Pakistan
por: Ali, Sajid, et al.
Publicado: (2014)

Association of the HLA-DQA1 and HLA-DQB1 Alleles in Type 2 Diabetes Mellitus and Diabetic Nephropathy in the Han Ethnicity of China
por: Ma, Ze-Jun, et al.
Publicado: (2013)

Revival of Cancer Registration in Karachi, Pakistan
por: Qureshi, Muhammad Asif
Publicado: (2021)

Correction: Type 2 Diabetes Risk Allele Loci in the Qatari Population
por: O’Beirne, Sarah L., et al.
Publicado: (2016)

Medicinal flora and ethnoecological knowledge in the Naran Valley, Western Himalaya, Pakistan
por: Khan, Shujaul M, et al.
Publicado: (2013)

Current Practices and Perceived Role of Community Pharmacists in Type 2 Diabetes Services in Pakistan
por: Arif, Rasikh, et al.
Publicado: (2023)

Prevalence of Type 2 Diabetes Mellitus in Adult Population of Pakistan: A Meta-Analysis of Prospective Cross-Sectional Surveys
por: Adnan, Muhammad, et al.
Publicado: (2020)

Occurrence of Aflatoxins Contamination in Brown Rice from Pakistan
por: ASGHAR, Muhammad Asif, et al.
Publicado: (2014)

Identification of soil type in Pakistan using remote sensing and machine learning
por: Ul Haq, Yasin, et al.
Publicado: (2022)

Diabetes Prevalence Survey of Pakistan (DPS-PAK): prevalence of type 2 diabetes mellitus and prediabetes using HbA1c: a population-based survey from Pakistan
por: Aamir, Azizul Hasan, et al.
Publicado: (2019)

Predictors of Child’s Health in Pakistan and the Moderating Role of Birth Spacing
por: Asif, Muhammad Farhan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3hjl2no6sfvha5igb7k53rpqbf