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mtDNA Maintenance and Alterations in the Pathogenesis of Neurodegenerative Diseases

Considerable evidence indicates that the semiautonomous organelles mitochondria play key roles in the progression of many neurodegenerative disorders. Mitochondrial DNA (mtDNA) encodes components of the OXPHOS complex but mutated mtDNA accumulates in cells with aging, which mirrors the increased pre...

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Detalles Bibliográficos
Autores principales: Shang, Dehao, Huang, Minghao, Wang, Biyao, Yan, Xu, Wu, Zhou, Zhang, Xinwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207910/
https://www.ncbi.nlm.nih.gov/pubmed/35950246
http://dx.doi.org/10.2174/1570159X20666220810114644