SPINK1 contributes to proliferation and clonal formation of HT29 cells through Beclin1 associated enhanced autophagy

We aimed to explore the molecular mechanism that were involved in SPINK1-induced proliferation and clonogenic survival of human colorectal carcinoma (CRC) HT29 cells. Initially, we generated HT29 cells either permanently silencing or overexpressing SPINK1 protein. The results showed that SPINK1 over...

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Detalles Bibliográficos
Autores principales: HU, NA, ZHANG, SHIQING, JIN, AQUAN, GUO, LIANYING, QU, ZHENYUN, WANG, JUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tech Science Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207951/
https://www.ncbi.nlm.nih.gov/pubmed/37305325
http://dx.doi.org/10.32604/or.2022.027058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207951/
https://www.ncbi.nlm.nih.gov/pubmed/37305325
http://dx.doi.org/10.32604/or.2022.027058

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