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SPINK1 contributes to proliferation and clonal formation of HT29 cells through Beclin1 associated enhanced autophagy
We aimed to explore the molecular mechanism that were involved in SPINK1-induced proliferation and clonogenic survival of human colorectal carcinoma (CRC) HT29 cells. Initially, we generated HT29 cells either permanently silencing or overexpressing SPINK1 protein. The results showed that SPINK1 over...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Tech Science Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207951/ https://www.ncbi.nlm.nih.gov/pubmed/37305325 http://dx.doi.org/10.32604/or.2022.027058 |