Heroin-Induced Leukoencephalopathy Leading to Locked-In Syndrome: A Case Report

Heroin-induced leukoencephalopathy (HLE) is a rare neurological sequela of heroin use. Heroin can be consumed through different routes such as inhalation, intravenous injection, and snorting. HLE cases have been reported via each route. However, heroin vapor inhalation has a higher rate of HLE and i...

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Detalles Bibliográficos
Autores principales: Shtembari, Jurgen, Shrestha, Dhan B, Zhang, Kaiyuan, Rengarajan, Dinesh, Joshi, Tilak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207984/
https://www.ncbi.nlm.nih.gov/pubmed/37228564
http://dx.doi.org/10.7759/cureus.38020
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author Shtembari, Jurgen
Shrestha, Dhan B
Zhang, Kaiyuan
Rengarajan, Dinesh
Joshi, Tilak
author_facet Shtembari, Jurgen
Shrestha, Dhan B
Zhang, Kaiyuan
Rengarajan, Dinesh
Joshi, Tilak
author_sort Shtembari, Jurgen
collection PubMed
description Heroin-induced leukoencephalopathy (HLE) is a rare neurological sequela of heroin use. Heroin can be consumed through different routes such as inhalation, intravenous injection, and snorting. HLE cases have been reported via each route. However, heroin vapor inhalation has a higher rate of HLE and is also known as “chasing the dragon syndrome.” We present a 65-year-old male who came unresponsive after heroin intoxication. During the hospital stay, he developed locked-in syndrome secondary to brain damage by HLE sequelae.
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spelling pubmed-102079842023-05-24 Heroin-Induced Leukoencephalopathy Leading to Locked-In Syndrome: A Case Report Shtembari, Jurgen Shrestha, Dhan B Zhang, Kaiyuan Rengarajan, Dinesh Joshi, Tilak Cureus Internal Medicine Heroin-induced leukoencephalopathy (HLE) is a rare neurological sequela of heroin use. Heroin can be consumed through different routes such as inhalation, intravenous injection, and snorting. HLE cases have been reported via each route. However, heroin vapor inhalation has a higher rate of HLE and is also known as “chasing the dragon syndrome.” We present a 65-year-old male who came unresponsive after heroin intoxication. During the hospital stay, he developed locked-in syndrome secondary to brain damage by HLE sequelae. Cureus 2023-04-23 /pmc/articles/PMC10207984/ /pubmed/37228564 http://dx.doi.org/10.7759/cureus.38020 Text en Copyright © 2023, Shtembari et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Shtembari, Jurgen
Shrestha, Dhan B
Zhang, Kaiyuan
Rengarajan, Dinesh
Joshi, Tilak
Heroin-Induced Leukoencephalopathy Leading to Locked-In Syndrome: A Case Report
title Heroin-Induced Leukoencephalopathy Leading to Locked-In Syndrome: A Case Report
title_full Heroin-Induced Leukoencephalopathy Leading to Locked-In Syndrome: A Case Report
title_fullStr Heroin-Induced Leukoencephalopathy Leading to Locked-In Syndrome: A Case Report
title_full_unstemmed Heroin-Induced Leukoencephalopathy Leading to Locked-In Syndrome: A Case Report
title_short Heroin-Induced Leukoencephalopathy Leading to Locked-In Syndrome: A Case Report
title_sort heroin-induced leukoencephalopathy leading to locked-in syndrome: a case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207984/
https://www.ncbi.nlm.nih.gov/pubmed/37228564
http://dx.doi.org/10.7759/cureus.38020
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