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Konjac glucomannan enhances 5-FU-induced cytotoxicity of hepatocellular carcinoma cells via TLR4/PERK/CHOP signaling to induce endoplasmic reticulum stress

5-Fluorouracil (5-FU) is a commonly used chemotherapeutic agent for various cancers. However, the drug resistance developed by tumor cells hinders the therapeutic effect. Konjac glucomannan (KGM) is indicated to sensitize 5-FU-resistant hepatocellular carcinoma (HCC) cells to 5-FU. In our study, we...

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Detalles Bibliográficos
Autores principales:	SHI, YONGKANG, MA, JUN, CHEN, KE, CHEN, BIN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Tech Science Press 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208023/ https://www.ncbi.nlm.nih.gov/pubmed/37304412 http://dx.doi.org/10.32604/or.2022.027584

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