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Computational docking and in vitro analysis identifies novel arylidene analogue FPMXY-14 against renal cancer cells by attenuating Akt

Targeted therapies are gaining global attention to tackle Renal Cancer (RC). This study aims to screen FPMXY-14 (novel arylidene analogue) for Akt inhibition by computational and in vitro methods. FPMXY-14 was subjected to proton NMR analysis and Mass spectrum analysis. Vero, HEK-293, Caki-1, and A4...

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Detalles Bibliográficos
Autores principales:	OTIFI, HASSAN M., ALSHYARBA, MISHARI, FAYI, MAJED AL, DERA, AYED A., RAJAGOPALAN, PRASANNA
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Tech Science Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208040/ https://www.ncbi.nlm.nih.gov/pubmed/37304673 http://dx.doi.org/10.32604/or.2022.03570

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