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Is autophagy induction by PARP inhibitors a target for therapeutic benefit?

PARP inhibitors have proven to be effective in conjunction with conventional therapeutics in the treatment of various solid as well as hematologic malignancies, particularly when the tumors are deficient in DNA repair pathways. However, as the case with other chemotherapeutic agents, their effective...

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Detalles Bibliográficos
Autores principales: ELSHAZLY, AHMED M., NGUYEN, TUONG VI V., GEWIRTZ, DAVID A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tech Science Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208061/
https://www.ncbi.nlm.nih.gov/pubmed/37304006
http://dx.doi.org/10.32604/or.2022.026459

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