Cargando…

Integrative multiomics analysis identifies a metastasis-related gene signature and the potential oncogenic role of EZR in breast cancer

Distant metastasis is a major cause of increased mortality in breast cancer patients, but the mechanisms underlying breast cancer metastasis remain poorly understood. In this study, we aimed to identify a metastasis-related gene (MRG) signature for predicting progression in breast cancer. By screeni...

Descripción completa

Detalles Bibliográficos
Autores principales:	XIAO, GUODONG, CHENG, FENG, YUAN, JING, LU, WEIPING, WANG, PEILI, FAN, HUIJIE
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Tech Science Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208079/ https://www.ncbi.nlm.nih.gov/pubmed/37304008 http://dx.doi.org/10.32604/or.2022.026616

Ejemplares similares

The interaction of lncRNA EZR-AS1 with SMYD3 maintains overexpression of EZR in ESCC cells
por: Zhang, Xiao-Dan, et al.
Publicado: (2018)

EZR promotes pancreatic cancer proliferation and metastasis by activating FAK/AKT signaling pathway
por: Xu, Jian, et al.
Publicado: (2021)

Long noncoding RNA EZR-AS1 promotes tumor growth and metastasis by modulating Wnt/β-catenin pathway in breast cancer
por: Bai, Yu, et al.
Publicado: (2018)

EzrA Contributes to the Regulation of Cell Size in Staphylococcus aureus
por: Jorge, Ana M., et al.
Publicado: (2011)

Functional Domain Analysis of the Cell Division Inhibitor EzrA
por: Land, Adrian D., et al.
Publicado: (2014)

High expression of EZR (ezrin) gene is correlated with the poor overall survival of breast cancer patients
por: Zhang, Rongju, et al.
Publicado: (2019)

Investigation of the freely available easy-to-use software ‘EZR' for medical statistics
por: Kanda, Y
Publicado: (2013)

Integrative multiomics-histopathology analysis for breast cancer classification
por: Ektefaie, Yasha, et al.
Publicado: (2021)

EzrA: a spectrin-like scaffold in the bacterial cell division machinery
por: Cleverley, Robert, et al.
Publicado: (2015)

The Activity of KIF14, Mieap, and EZR in a New Type of the Invasive Component, Torpedo-Like Structures, Predetermines the Metastatic Potential of Breast Cancer
por: Gerashchenko, Tatiana S., et al.
Publicado: (2020)

TMED3 promotes the progression and development of lung squamous cell carcinoma by regulating EZR
por: Xie, An, et al.
Publicado: (2021)

Multiomics signatures of type 1 diabetes with and without albuminuria
por: Clos-Garcia, Marc, et al.
Publicado: (2022)

Multiomics and machine-learning identify novel transcriptional and mutational signatures in amyotrophic lateral sclerosis
por: Catanese, Alberto, et al.
Publicado: (2023)

An Integrated Multiomics Approach to Identify Candidate Antigens for Serodiagnosis of Human Onchocerciasis
por: McNulty, Samantha N., et al.
Publicado: (2015)

Embracing Integrative Multiomics Approaches
por: Rotroff, Daniel M., et al.
Publicado: (2016)

An integrative multiomics analysis identifies putative causal genes for COVID-19 severity
por: Wu, Lang, et al.
Publicado: (2021)

‘Breast Cancer Resistance Likelihood and Personalized Treatment Through Integrated Multiomics’
por: Mehmood, Sabba, et al.
Publicado: (2022)

Long Noncoding RNA EZR-AS1 Regulates the Proliferation, Migration, and Apoptosis of Human Venous Endothelial Cells via SMYD3
por: You, Ganhua, et al.
Publicado: (2020)

Tetracycline hypersensitivity of an ezrA mutant links GalE and TseB (YpmB) to cell division
por: Gamba, Pamela, et al.
Publicado: (2015)

Hypoxia-induced autophagy drives colorectal cancer initiation and progression by activating the PRKC/PKC-EZR (ezrin) pathway
por: Qureshi-Baig, Komal, et al.
Publicado: (2019)

Multiomic signatures of body mass index identify heterogeneous health phenotypes and responses to a lifestyle intervention
por: Watanabe, Kengo, et al.
Publicado: (2023)

Multiomics-empowered Deep Phenotyping of Ulcerative Colitis Identifies Biomarker Signatures Reporting Functional Remission States
por: Janker, Lukas, et al.
Publicado: (2023)

Multiomics integration-based molecular characterizations of COVID-19
por: Li, Chuan-Xing, et al.
Publicado: (2021)

Integrated Multiomics Analysis Identifies a Novel Biomarker Associated with Prognosis in Intracerebral Hemorrhage
por: Shen, Yiqing, et al.
Publicado: (2021)

Multiomics analysis reveals CT83 is the most specific gene for triple negative breast cancer and its hypomethylation is oncogenic in breast cancer
por: Chen, Chen, et al.
Publicado: (2021)

Long-term progression-free survival in an advanced lung adenocarcinoma patient harboring EZR-ROS1 rearrangement: a case report
por: Dong, Liang, et al.
Publicado: (2018)

Integrative single-cell multiomics analyses dissect molecular signatures of intratumoral heterogeneities and differentiation states of human gastric cancer
por: Bian, Shuhui, et al.
Publicado: (2023)

Exploring the Potential of Multiomics and Other Integrative Approaches for Improving Waterlogging Tolerance in Plants
por: Tyagi, Anshika, et al.
Publicado: (2023)

Multiomic Integration of Public Oncology Databases in Bioconductor
por: Ramos, Marcel, et al.
Publicado: (2020)

Executable Network Models of Integrated Multiomics Data
por: Palshikar, Mukta G., et al.
Publicado: (2023)

Potential of multiomics technology in precision medicine
por: Putignani, Lorenza, et al.
Publicado: (2019)

Biological effects of negative air ions on human health and integrated multiomics to identify biomarkers: a literature review
por: Xiao, Sha, et al.
Publicado: (2023)

Multiomics Integrated Analysis Identifies SLC24A2 as a Potential Link between Type 2 Diabetes and Cancer
por: Bian, Qin, et al.
Publicado: (2022)

Integrated multiomics analysis identifies molecular landscape perturbations during hyperammonemia in skeletal muscle and myotubes
por: Welch, Nicole, et al.
Publicado: (2021)

Integrated Multiomics Analysis of Salivary Exosomes to Identify Biomarkers Associated with Changes in Mood States and Fatigue
por: Cohn, Whitaker, et al.
Publicado: (2022)

Integrative Multiomics Evaluation of IIDH1 Metabolic Enzyme as a Candidate Oncogene That is Correlated with Poor Prognosis and Immune Infiltration in Prostate Adenocarcinoma
por: Wen, Chen-Yueh, et al.
Publicado: (2022)

Unravelling triple-negative breast cancer molecular heterogeneity using an integrative multiomic analysis
por: Bareche, Y, et al.
Publicado: (2018)

Multiomics Profiling Reveals Signatures of Dysmetabolism in Urban Populations in Central India
por: Monaghan, Tanya M., et al.
Publicado: (2021)

A multiomics disease progression signature of low-risk ccRCC
por: Strauss, Philipp, et al.
Publicado: (2022)

Multiomics Topic Modeling for Breast Cancer Classification
por: Valle, Filippo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9a0502ko2hu2bu8dbv7he4ikhb