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IL-38 blockade induces anti-tumor immunity by abrogating tumor-mediated suppression of early immune activation
Immune checkpoint inhibitors that overcome T cell suppressive mechanisms in tumors have revolutionized the treatment of cancer but are only efficacious in a small subset of patients. Targeting suppressive mechanisms acting on innate immune cells could significantly improve the incidence of clinical...
Autores principales: | Dowling, John P., Nikitin, Pavel A., Shen, Fang, Shukla, Halley, Finn, James P., Patel, Nirja, Swider, Cezary, Bingaman-Steele, Jamie L., Nicolescu, Chris, Sikorski, Eden L, Greenawalt, Evan J., Morin, Michael J., Robinson, Matthew K., Lundgren, Karen, Harman, Benjamin C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208126/ https://www.ncbi.nlm.nih.gov/pubmed/37216961 http://dx.doi.org/10.1080/19420862.2023.2212673 |
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