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Higher Rates of Complicated Appendicitis During the COVID-19 Pandemic: A Year-to-Year Analysis

INTRODUCTION: The COVID-19 pandemic impacted presentation, management strategies, and patient outcomes of numerous medical conditions. The aim of this study is to perform a year-to-year comparison of clinical outcomes of patients with acute appendicitis (AA) before and during the pandemic. METHODS:...

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Autores principales: Kupietzky, Amram, Finkin, Miriam, Dover, Roi, Eliezer Lourie, Nachum Emil, Mordechai-heyn, Tzlil, Juster, Eyal Yonathan, Mazeh, Haggi, Mizrahi, Ido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208264/
https://www.ncbi.nlm.nih.gov/pubmed/37329625
http://dx.doi.org/10.1016/j.jss.2023.05.007
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author Kupietzky, Amram
Finkin, Miriam
Dover, Roi
Eliezer Lourie, Nachum Emil
Mordechai-heyn, Tzlil
Juster, Eyal Yonathan
Mazeh, Haggi
Mizrahi, Ido
author_facet Kupietzky, Amram
Finkin, Miriam
Dover, Roi
Eliezer Lourie, Nachum Emil
Mordechai-heyn, Tzlil
Juster, Eyal Yonathan
Mazeh, Haggi
Mizrahi, Ido
author_sort Kupietzky, Amram
collection PubMed
description INTRODUCTION: The COVID-19 pandemic impacted presentation, management strategies, and patient outcomes of numerous medical conditions. The aim of this study is to perform a year-to-year comparison of clinical outcomes of patients with acute appendicitis (AA) before and during the pandemic. METHODS: Patients treated for AA during the initial 12-mo period of the pandemic at our institute were compared to those treated for AA during the 12-mo period before. Clinical and laboratory parameters, treatment strategies, intraoperative findings, pathology reports, and postoperative outcomes were compared. RESULTS: During the study period, 541 patients presented with AA. The median (interquartile range) age was 28 (21-40) y and 292 (54%) were males. 262 (48%) patients presented during the pre-COVID-19 period, while 279 patients (52%) presented during the COVID 19 pandemic. The groups were comparable for baseline clinical data and imaging results upon index admission. There was no significant difference in rate of nonoperative treatment between the Pre-COVID-19 and During-COVID-19 eras (51% versus 53%, P = 0.6) as well as the success rate of such treatment (95.4% versus 96.4%, P = 0.3). Significantly more patients presented with a periappendicular abscess during COVID-19 (4.6% versus 1.1%, P = 0.01) and median (interquartile range) operative time was significantly longer (78 (61-90) versus 32.5 (27-45) min, P < 0.001). Pathology reports revealed a higher rate of perforated appendicitis during COVID-19 (27.4% versus 10.2%, P < 0.001). CONCLUSIONS: Patients with AA present with higher rates of perforated and complicated appendicitis during the COVID-19 pandemic. The success rates of nonoperative management in selected patients with noncomplicated AA did not change during the pandemic and is a safe, feasible, option.
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spelling pubmed-102082642023-05-25 Higher Rates of Complicated Appendicitis During the COVID-19 Pandemic: A Year-to-Year Analysis Kupietzky, Amram Finkin, Miriam Dover, Roi Eliezer Lourie, Nachum Emil Mordechai-heyn, Tzlil Juster, Eyal Yonathan Mazeh, Haggi Mizrahi, Ido J Surg Res Article INTRODUCTION: The COVID-19 pandemic impacted presentation, management strategies, and patient outcomes of numerous medical conditions. The aim of this study is to perform a year-to-year comparison of clinical outcomes of patients with acute appendicitis (AA) before and during the pandemic. METHODS: Patients treated for AA during the initial 12-mo period of the pandemic at our institute were compared to those treated for AA during the 12-mo period before. Clinical and laboratory parameters, treatment strategies, intraoperative findings, pathology reports, and postoperative outcomes were compared. RESULTS: During the study period, 541 patients presented with AA. The median (interquartile range) age was 28 (21-40) y and 292 (54%) were males. 262 (48%) patients presented during the pre-COVID-19 period, while 279 patients (52%) presented during the COVID 19 pandemic. The groups were comparable for baseline clinical data and imaging results upon index admission. There was no significant difference in rate of nonoperative treatment between the Pre-COVID-19 and During-COVID-19 eras (51% versus 53%, P = 0.6) as well as the success rate of such treatment (95.4% versus 96.4%, P = 0.3). Significantly more patients presented with a periappendicular abscess during COVID-19 (4.6% versus 1.1%, P = 0.01) and median (interquartile range) operative time was significantly longer (78 (61-90) versus 32.5 (27-45) min, P < 0.001). Pathology reports revealed a higher rate of perforated appendicitis during COVID-19 (27.4% versus 10.2%, P < 0.001). CONCLUSIONS: Patients with AA present with higher rates of perforated and complicated appendicitis during the COVID-19 pandemic. The success rates of nonoperative management in selected patients with noncomplicated AA did not change during the pandemic and is a safe, feasible, option. Elsevier Inc. 2023-10 2023-05-24 /pmc/articles/PMC10208264/ /pubmed/37329625 http://dx.doi.org/10.1016/j.jss.2023.05.007 Text en © 2023 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Kupietzky, Amram
Finkin, Miriam
Dover, Roi
Eliezer Lourie, Nachum Emil
Mordechai-heyn, Tzlil
Juster, Eyal Yonathan
Mazeh, Haggi
Mizrahi, Ido
Higher Rates of Complicated Appendicitis During the COVID-19 Pandemic: A Year-to-Year Analysis
title Higher Rates of Complicated Appendicitis During the COVID-19 Pandemic: A Year-to-Year Analysis
title_full Higher Rates of Complicated Appendicitis During the COVID-19 Pandemic: A Year-to-Year Analysis
title_fullStr Higher Rates of Complicated Appendicitis During the COVID-19 Pandemic: A Year-to-Year Analysis
title_full_unstemmed Higher Rates of Complicated Appendicitis During the COVID-19 Pandemic: A Year-to-Year Analysis
title_short Higher Rates of Complicated Appendicitis During the COVID-19 Pandemic: A Year-to-Year Analysis
title_sort higher rates of complicated appendicitis during the covid-19 pandemic: a year-to-year analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208264/
https://www.ncbi.nlm.nih.gov/pubmed/37329625
http://dx.doi.org/10.1016/j.jss.2023.05.007
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