Cargando…

α-Ketoglutarate stimulates cell growth through the improvement of glucose and glutamine metabolism in C2C12 cell culture

INTRODUCTION: Cellular adaptation to physical training and energy metabolism play an important role during physical exercise. This study sought to investigate the effects of α-KG on cell growth and energy metabolism in C2C12 cell culture. METHODS: C2C12 cells were cultured in media pretreated withou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Bingquan, Liu, Yuefei, Steinacker, Jürgen Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Nutrition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208397/ https://www.ncbi.nlm.nih.gov/pubmed/37234553 http://dx.doi.org/10.3389/fnut.2023.1145236

Ejemplares similares

NMR-Based Metabolic Profiling of the Effects of α-Ketoglutarate Supplementation on Energy-Deficient C2C12 Myotubes
por: Li, Yantong, et al.
Publicado: (2023)

Ornithine α-Ketoglutarate Alleviates Inflammation via Regulating Ileal Mucosa Microbiota and Metabolites in Enterotoxigenic Escherichia coli-Infected Pigs
por: Li, Yuying, et al.
Publicado: (2022)

Activated protein C modulates T-cell metabolism and epigenetic FOXP3 induction via α-ketoglutarate
por: Gupta, Dheerendra, et al.
Publicado: (2023)

The Regulatory Role of α-Ketoglutarate Metabolism in Macrophages
por: Liu, Shaojuan, et al.
Publicado: (2021)

Improved training tolerance by supplementation with α-Keto acids in untrained young adults: a randomized, double blind, placebo-controlled trial
por: Liu, Yuefei, et al.
Publicado: (2012)

Metabolic regulation of pluripotency and germ cell fate through α‐ketoglutarate
por: Tischler, Julia, et al.
Publicado: (2018)

NMR-Based Metabolomic Analysis for the Effects of α-Ketoglutarate Supplementation on C2C12 Myoblasts in Different Energy States
por: Li, Yantong, et al.
Publicado: (2021)

The α-ketoglutarate dehydrogenase complex in cancer metabolic plasticity
por: Vatrinet, Renaud, et al.
Publicado: (2017)

Glutamate and α-ketoglutarate: key players in glioma metabolism
por: Maus, Andreas, et al.
Publicado: (2016)

α-Ketoglutarate inhibits autophagy
por: Baracco, Elisa Elena, et al.
Publicado: (2019)

Dietary Vitamin C Intake Is Associated With Improved Liver Function and Glucose Metabolism in Chinese Adults
por: Luo, Xiaoqin, et al.
Publicado: (2022)

Serum-free alginate-C2C12 cells microcapsule as a model of alternative animal protein source
por: Scheffold, Jana, et al.
Publicado: (2023)

Spontaneous hydrolysis and spurious metabolic properties of α-ketoglutarate esters
por: Parker, Seth J., et al.
Publicado: (2021)

A metabolic shift toward glycolysis enables cancer cells to maintain survival upon concomitant glutamine deprivation and V-ATPase inhibition
por: Lengauer, Florian, et al.
Publicado: (2023)

Effect of Alpha-Ketoglutarate on Growth and Metabolism of Cells Cultured on Three-Dimensional Cryogel Matrix
por: Singh, Deepti, et al.
Publicado: (2013)

Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells
por: Carey, Bryce W., et al.
Publicado: (2014)

α-Ketoglutarate Promotes Pancreatic Progenitor-Like Cell Proliferation
por: Song, Jing, et al.
Publicado: (2018)

In Situ Monitoring of Intracellular Glucose and Glutamine in CHO Cell Culture
por: Behjousiar, Alireza, et al.
Publicado: (2012)

Heterogeneous cellular effects of α-ketoglutarate esters
por: Galluzzi, Lorenzo
Publicado: (2019)

A nutritional supplement based on a synbiotic combination of Bacillus subtilis DSM 32315 and L-alanyl-L-glutamine improves glucose metabolism in healthy prediabetic subjects – A real-life post-marketing study
por: Kordowski, Anna, et al.
Publicado: (2022)

Host and Clostridioides difficile-Response Modulated by Micronutrients and Glutamine: An Overview
por: Loureiro, Andréa V., et al.
Publicado: (2022)

Antimetabolic Effects of Polyphenols in Breast Cancer Cells: Focus on Glucose Uptake and Metabolism
por: Keating, Elisa, et al.
Publicado: (2018)

Dietary glutamine, glutamic acid and nucleotide supplementation accelerate carbon turnover (δ(13)C) on stomach of weaned piglets
por: Assoni, Amanda D., et al.
Publicado: (2017)

Lipid and glucose metabolism in senescence
por: Liu, Bin, et al.
Publicado: (2023)

The Fate of Glutamine in Human Metabolism. The Interplay with Glucose in Proliferating Cells
por: Mazat, Jean-Pierre, et al.
Publicado: (2019)

Changes in Glucose and Glutamine Lymphocyte Metabolisms Induced by Type I Interferon α
por: Navarro, Francisco, et al.
Publicado: (2010)

Glucose- and glutamine-fueled stabilization of C-Myc is required for T-cell proliferation and malignant transformation
por: Gabriel, SS, et al.
Publicado: (2016)

The mechanism and role of intracellular α-ketoglutarate reduction in hepatic stellate cell activation
por: Zhao, Jianjian, et al.
Publicado: (2020)

Glucose variability in 6–12-month-old healthy infants
por: Hauschild, Michael, et al.
Publicado: (2023)

Evaluating the Diagnostic Value of a Combined Indicator of Vitamin B(12) Status (cB(12)) Throughout Pregnancy
por: Dib, Marie-Joe, et al.
Publicado: (2022)

The association of dietary glutamine supplementation with the development of high salt-induced hypertension in rats
por: Yang, Liu, et al.
Publicado: (2022)

Contributions of Fat and Carbohydrate Metabolism to Glucose Homeostasis in Childhood Change With Age and Puberty: A 12-Years Cohort Study (EARLYBIRD 77)
por: Cominetti, Ornella, et al.
Publicado: (2020)

Dietary glutamine, glutamate, and aspartate supplementation improves hepatic lipid metabolism in post-weaning piglets
por: Qi, Ming, et al.
Publicado: (2020)

Meta-analysis of Glutamine on Immune Function and Post-Operative Complications of Patients With Colorectal Cancer
por: Yang, Tao, et al.
Publicado: (2021)

Efficacy of Glutamine in Treating Severe Acute Pancreatitis: A Systematic Review and Meta-Analysis
por: Dong, Shi, et al.
Publicado: (2022)

Matcha green tea targets the gut–liver axis to alleviate obesity and metabolic disorders induced by a high-fat diet
por: Wang, Yuefei, et al.
Publicado: (2022)

Protection of Pepper Plants from Drought by Microbacterium sp. 3J1 by Modulation of the Plant's Glutamine and α-ketoglutarate Content: A Comparative Metabolomics Approach
por: Vílchez, Juan I., et al.
Publicado: (2018)

The role of α-ketoglutarate and the hypoxia sensing pathway in the regulation of pancreatic β-cell function
por: Hoang, M., et al.
Publicado: (2020)

Directed-Mutagenesis of Flavobacterium meningosepticum Prolyl-Oligopeptidase and a Glutamine-Specific Endopeptidase From Barley
por: Osorio, Claudia E., et al.
Publicado: (2020)

Glutamine Supplementation Enhances the Effects of a Low FODMAP Diet in Irritable Bowel Syndrome Management
por: Rastgoo, Samira, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9kredmll7ndcd0h48kvchm2m27