Upregulation of LAG3 modulates the immune imbalance of CD4(+) T-cell subsets and exacerbates disease progression in patients with alveolar echinococcosis and a mouse model

Infection with the cestode Echinococcus multilocularis (E. multilocularis) causes alveolar echinococcosis (AE), a tumor-like disease predominantly affecting the liver but able to spread to any organ. T cells develop functional defects during chronic E. multilocularis infection, mostly due to upregul...

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Detalles Bibliográficos
Autores principales: Li, Dewei, Ainiwaer, Abidan, Zheng, Xuran, Wang, Maolin, Shi, Yang, Rousu, Zibigu, Hou, Xinling, Kang, Xuejiao, Maimaiti, Muesier, Wang, Hui, Li, Jing, Zhang, Chuanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208502/
https://www.ncbi.nlm.nih.gov/pubmed/37172058
http://dx.doi.org/10.1371/journal.ppat.1011396

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