Cargando…

Gitelman Syndrome Presenting with Cerebellar Ataxia and Tetany

Gitelman syndrome (GS) is salt-losing tubulopathy characterized by hypokalemia, hypomagnesemia, hypocalciuria, hyperreninemia, hyperaldosteronemia, metabolic alkalosis, and rarely hypocalcemia. Here, we describe the case of a 54-year-old man who presented with cerebellar signs and tetany. On investi...

Descripción completa

Detalles Bibliográficos
Autores principales: Pandya, Shalini, Shah, Shalin, Dalal, Sonal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208539/
https://www.ncbi.nlm.nih.gov/pubmed/37234429
http://dx.doi.org/10.4103/ijn.ijn_401_21
_version_ 1785046689977991168
author Pandya, Shalini
Shah, Shalin
Dalal, Sonal
author_facet Pandya, Shalini
Shah, Shalin
Dalal, Sonal
author_sort Pandya, Shalini
collection PubMed
description Gitelman syndrome (GS) is salt-losing tubulopathy characterized by hypokalemia, hypomagnesemia, hypocalciuria, hyperreninemia, hyperaldosteronemia, metabolic alkalosis, and rarely hypocalcemia. Here, we describe the case of a 54-year-old man who presented with cerebellar signs and tetany. On investigation, he was found to have hypokalemia, hypocalcemia, hypomagnesemia, metabolic alkalosis, and high urinary chloride levels. On correction of metabolic parameters, he became asymptomatic. In cases of unexplained recurrent hypokalemia, hypocalcemia and hypomagnesemia, the diagnosis of GS should be considered.
format Online
Article
Text
id pubmed-10208539
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-102085392023-05-25 Gitelman Syndrome Presenting with Cerebellar Ataxia and Tetany Pandya, Shalini Shah, Shalin Dalal, Sonal Indian J Nephrol Case Report Gitelman syndrome (GS) is salt-losing tubulopathy characterized by hypokalemia, hypomagnesemia, hypocalciuria, hyperreninemia, hyperaldosteronemia, metabolic alkalosis, and rarely hypocalcemia. Here, we describe the case of a 54-year-old man who presented with cerebellar signs and tetany. On investigation, he was found to have hypokalemia, hypocalcemia, hypomagnesemia, metabolic alkalosis, and high urinary chloride levels. On correction of metabolic parameters, he became asymptomatic. In cases of unexplained recurrent hypokalemia, hypocalcemia and hypomagnesemia, the diagnosis of GS should be considered. Wolters Kluwer - Medknow 2023 2022-11-22 /pmc/articles/PMC10208539/ /pubmed/37234429 http://dx.doi.org/10.4103/ijn.ijn_401_21 Text en Copyright: © 2022 Indian Journal of Nephrology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Pandya, Shalini
Shah, Shalin
Dalal, Sonal
Gitelman Syndrome Presenting with Cerebellar Ataxia and Tetany
title Gitelman Syndrome Presenting with Cerebellar Ataxia and Tetany
title_full Gitelman Syndrome Presenting with Cerebellar Ataxia and Tetany
title_fullStr Gitelman Syndrome Presenting with Cerebellar Ataxia and Tetany
title_full_unstemmed Gitelman Syndrome Presenting with Cerebellar Ataxia and Tetany
title_short Gitelman Syndrome Presenting with Cerebellar Ataxia and Tetany
title_sort gitelman syndrome presenting with cerebellar ataxia and tetany
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208539/
https://www.ncbi.nlm.nih.gov/pubmed/37234429
http://dx.doi.org/10.4103/ijn.ijn_401_21
work_keys_str_mv AT pandyashalini gitelmansyndromepresentingwithcerebellarataxiaandtetany
AT shahshalin gitelmansyndromepresentingwithcerebellarataxiaandtetany
AT dalalsonal gitelmansyndromepresentingwithcerebellarataxiaandtetany