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Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents

Several antibody therapeutics have been developed against SARS-CoV-2; however, they have attenuated neutralizing ability against variants. In this study, we generated multiple broadly neutralizing antibodies from B cells of convalescents, by using two types of receptor-binding domains, Wuhan strain...

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Detalles Bibliográficos
Autores principales:	Takeshita, Masaru, Fukuyama, Hidehiro, Kamada, Katsuhiko, Matsumoto, Takehisa, Makino-Okamura, Chieko, Lin, Qingshun, Sakuma, Machie, Kawahara, Eiki, Yamazaki, Isato, Uchikubo-Kamo, Tomomi, Tomabechi, Yuri, Hanada, Kazuharu, Hisano, Tamao, Moriyama, Saya, Takahashi, Yoshimasa, Ito, Mutsumi, Imai, Masaki, Maemura, Tadashi, Furusawa, Yuri, Yamayoshi, Seiya, Kawaoka, Yoshihiro, Shirouzu, Mikako, Ishii, Makoto, Saya, Hideyuki, Kondo, Yasushi, Kaneko, Yuko, Suzuki, Katsuya, Fukunaga, Koichi, Takeuchi, Tsutomu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208659/ https://www.ncbi.nlm.nih.gov/pubmed/37288342 http://dx.doi.org/10.1016/j.isci.2023.106955

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