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Spermidine Retarded the Senescence of Multipotent Mesenchymal Stromal Cells In Vitro and In Vivo through SIRT3-Mediated Antioxidation

Multipotent mesenchymal stromal cells (MSCs) expand in vitro and undergo replicative senescence, thereby restricting their clinical utilization. Thus, an effective strategy is required to impede MSC senescence. Since spermidine (SPD) supplementation can prolong the lifespan of yeast by inhibiting ox...

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Detalles Bibliográficos
Autores principales: Huang, Hua, Zhang, Wen, Su, Junjie, Zhou, Bisheng, Han, Qingjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208764/
https://www.ncbi.nlm.nih.gov/pubmed/37234959
http://dx.doi.org/10.1155/2023/9672658

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