Silencing of microRNA-106b-5p prevents doxorubicin-mediated cardiotoxicity through modulation of the PR55α/YY1/sST2 signaling axis

Clinical use of doxorubicin (Dox), an anthracycline with potent anti-tumor effects, is limited because of its highly chemotherapy-induced cardiotoxicity (CIC). After myocardial infarction (MI), we have recently identified Yin Yang-1 (YY1) and histone deacetylase 4 (HDAC4) as two factors involved in...

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Detalles Bibliográficos
Autores principales: Lax, Antonio, Soler, Fernando, Fernandez del Palacio, Maria Josefa, Pascual-Oliver, Silvia, Ballester, Miriam Ruiz, Fuster, Jose Javier, Pascual-Figal, Domingo, Asensio-Lopez, Maria del Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208836/
https://www.ncbi.nlm.nih.gov/pubmed/37234747
http://dx.doi.org/10.1016/j.omtn.2023.04.031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208836/
https://www.ncbi.nlm.nih.gov/pubmed/37234747
http://dx.doi.org/10.1016/j.omtn.2023.04.031

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