Sphingosine-1-phosphate derived from PRP-Exos promotes angiogenesis in diabetic wound healing via the S1PR1/AKT/FN1 signalling pathway

BACKGROUND: Sphingosine-1-phosphate (S1P), a key regulator of vascular homeostasis and angiogenesis, is enriched in exosomes derived from platelet-rich plasma (PRP-Exos). However, the potential role of PRP-Exos-S1P in diabetic wound healing remains unclear. In this study, we investigated the underly...

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Detalles Bibliográficos
Autores principales: Chen, Tianyi, Song, Peiyang, He, Min, Rui, Shunli, Duan, Xiaodong, Ma, Yu, Armstrong, David G, Deng, Wuquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208895/
https://www.ncbi.nlm.nih.gov/pubmed/37251708
http://dx.doi.org/10.1093/burnst/tkad003

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