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Structural basis of catalytic activation in human splicing

Pre-mRNA splicing follows a pathway driven by ATP-dependent RNA helicases. A crucial event of the splicing pathway is the catalytic activation, which takes place at the transition between the activated B(act) and the branching-competent B(*) spliceosomes. Catalytic activation occurs through an ATP-d...

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Detalles Bibliográficos
Autores principales:	Schmitzová, Jana, Cretu, Constantin, Dienemann, Christian, Urlaub, Henning, Pena, Vladimir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208982/ https://www.ncbi.nlm.nih.gov/pubmed/37165190 http://dx.doi.org/10.1038/s41586-023-06049-w

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