Two C18 hydroxy-cyclohexenone fatty acids from mammalian epidermis: Potential relation to 12R-lipoxygenase and covalent binding of ceramides

A key requirement in forming the water permeability barrier in the mammalian epidermis is the oxidation of linoleate esterified in a skin-specific acylceramide by the sequential actions of 12R-lipoxygenase, epidermal lipoxygenase-3, and the epoxyalcohol dehydrogenase SDR9C7 (short-chain dehydrogenas...

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Detalles Bibliográficos
Autores principales: Brash, Alan R., Noguchi, Saori, Boeglin, William E., Calcutt, M. Wade, Stec, Donald F., Schneider, Claus, Meyer, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209020/
https://www.ncbi.nlm.nih.gov/pubmed/37086788
http://dx.doi.org/10.1016/j.jbc.2023.104739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209020/
https://www.ncbi.nlm.nih.gov/pubmed/37086788
http://dx.doi.org/10.1016/j.jbc.2023.104739

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