Cargando…

Two C18 hydroxy-cyclohexenone fatty acids from mammalian epidermis: Potential relation to 12R-lipoxygenase and covalent binding of ceramides

A key requirement in forming the water permeability barrier in the mammalian epidermis is the oxidation of linoleate esterified in a skin-specific acylceramide by the sequential actions of 12R-lipoxygenase, epidermal lipoxygenase-3, and the epoxyalcohol dehydrogenase SDR9C7 (short-chain dehydrogenas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brash, Alan R., Noguchi, Saori, Boeglin, William E., Calcutt, M. Wade, Stec, Donald F., Schneider, Claus, Meyer, Jason M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209020/ https://www.ncbi.nlm.nih.gov/pubmed/37086788 http://dx.doi.org/10.1016/j.jbc.2023.104739

Ejemplares similares

The Precise Structures and Stereochemistry of Trihydroxy-linoleates Esterified in Human and Porcine Epidermis and Their Significance in Skin Barrier Function: IMPLICATION OF AN EPOXIDE HYDROLASE IN THE TRANSFORMATIONS OF LINOLEATE
por: Chiba, Takahito, et al.
Publicado: (2016)

Monolayer autoxidation of arachidonic acid to epoxyeicosatrienoic acids as a model of their potential formation in cell membranes
por: Weiny, James A., et al.
Publicado: (2021)

Analysis of 12/15-lipoxygenase metabolism of EPA and DHA with special attention to authentication of docosatrienes
por: Jin, Jing, et al.
Publicado: (2021)

Role of Omega-Hydroxy Ceramides in Epidermis: Biosynthesis, Barrier Integrity and Analyzing Method
por: Ge, Fei, et al.
Publicado: (2023)

Synthesis of the bis(cyclohexenone) core of (−)-lomaiviticin A
por: Rose, John A., et al.
Publicado: (2020)

Ceramides and Cell Signaling Molecules in Psoriatic Epidermis: Reduced Levels of Ceramides, PKC-α, and JNK
por: Lew, Bark-Lynn, et al.
Publicado: (2006)

Cyclization of 5-hexynoic acid to 3-alkoxy-2-cyclohexenones
por: Hylden, Anne T, et al.
Publicado: (2011)

Biosynthetic Crossover of 5-Lipoxygenase and Cyclooxygenase-2 Yields 5-Hydroxy-PGE(2) and 5-Hydroxy-PGD(2)
por: Nakashima, Fumie, et al.
Publicado: (2021)

The permeability barrier in mammalian epidermis
Publicado: (1975)

Stereospecific Synthesis of Cyclohexenone Acids by [3,3]-Sigmatropic Rearrangement Route
por: Eronen, Aleksi, et al.
Publicado: (2023)

Taurine accelerates the synthesis of ceramides and hyaluronic acid in cultured epidermis and dermal fibroblasts
por: Yoshimura, Tomohisa, et al.
Publicado: (2023)

Targeting Mammalian 5-Lipoxygenase by Dietary Phenolics as an Anti-Inflammatory Mechanism: A Systematic Review
por: Giménez-Bastida, Juan Antonio, et al.
Publicado: (2021)

Mammalian Epidermis: A Compendium of Lipid Functionality
por: Vietri Rudan, Matteo, et al.
Publicado: (2022)

Epoxide hydrolase 3 (Ephx3) gene disruption reduces ceramide linoleate epoxide hydrolysis and impairs skin barrier function
por: Edin, Matthew L., et al.
Publicado: (2021)

One-pot Fluorination and Organocatalytic Robinson Annulation for Asymmetric Synthesis of Mono- and Difluorinated Cyclohexenones
por: Huang, Xin, et al.
Publicado: (2018)

BIMP‐Catalyzed 1,3‐Prototropic Shift for the Highly Enantioselective Synthesis of Conjugated Cyclohexenones
por: Golec, Jonathan C., et al.
Publicado: (2020)

Toxicological Evaluation of Novel Cyclohexenone Derivative in an Animal Model through Histopathological and Biochemical Techniques
por: Kamil, Muhammad, et al.
Publicado: (2021)

Activation of 2‐Cyclohexenone by BF(3) Coordination: Mechanistic Insights from Theory and Experiment
por: Peschel, Martin T., et al.
Publicado: (2021)

Recombinant PNPLA1 catalyzes the synthesis of acylceramides and acyl acids with selective incorporation of linoleic acid
por: Meyer, Jason M., et al.
Publicado: (2023)

Molecular ligand modulation of palladium nanocatalysts for highly efficient and robust heterogeneous oxidation of cyclohexenone to phenol
por: Xue, Teng, et al.
Publicado: (2017)

Platinum-Catalyzed Hydrative Cyclization of 1,6-Diynes for the Synthesis of 3,5-Substituted Conjugated Cyclohexenones
por: Zhang, Chen, et al.
Publicado: (2010)

Enantiocontrolled Preparation of ϒ-Substituted Cyclohexenones: Synthesis and Kinase Activity Assays of Cyclopropyl-Fused Cyclohexane Nucleosides
por: Jurado, Sergio, et al.
Publicado: (2022)

Sulfatide with ceramide composed of phytosphingosine (t18:0) and 2-hydroxy FAs in renal intercalated cells
por: Nakashima, Keiko, et al.
Publicado: (2022)

Stereoselective Double Reduction of 3-Methyl-2-cyclohexenone, by Use of Palladium and Platinum Nanoparticles, in Tandem with Alcohol Dehydrogenase
por: Coccia, Francesca, et al.
Publicado: (2018)

Synergy of R-(–)carvone and cyclohexenone-based carbasugar precursors with antibiotics to enhance antibiotic potency and inhibit biofilm formation
por: Riester, Oliver, et al.
Publicado: (2022)

Exploring the 2′-Hydroxy-Chalcone Framework for the Development of Dual Antioxidant and Soybean Lipoxygenase Inhibitory Agents
por: Kostopoulou, Ioanna, et al.
Publicado: (2021)

The Epidermis
por: Savin, Ronald C.
Publicado: (1965)

ω-O-Acylceramides but not ω-hydroxy ceramides are required for healthy lamellar phase architecture of skin barrier lipids
por: Opálka, Lukáš, et al.
Publicado: (2022)

Biosynthesis of the Novel Endogenous 15-Lipoxygenase Metabolites N-13-Hydroxy-octodecadienoyl-ethanolamine and 13-Hydroxy-octodecadienoyl-glycerol by Human Neutrophils and Eosinophils
por: Archambault, Anne-Sophie, et al.
Publicado: (2021)

4,8-Sphingadienine and 4-hydroxy-8-sphingenine activate ceramide production in the skin
por: Shirakura, Yoshiyuki, et al.
Publicado: (2012)

Epithelial geometry regulates spindle orientation and progenitor fate during formation of the mammalian epidermis
por: Box, Kimberly, et al.
Publicado: (2019)

Tumours of the Epidermis
por: MacKie, R.M.
Publicado: (1992)

Squibbs’ Epidermis
Publicado: (1886)

Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis
por: Jensen, Kim B., et al.
Publicado: (2009)

Enhanced Triacylglycerol Content and Gene Expression for Triacylglycerol Metabolism, Acyl-Ceramide Synthesis, and Corneocyte Lipid Formation in the Epidermis of Borage Oil Fed Guinea Pigs
por: Lee, Ju-Young, et al.
Publicado: (2019)

Age- and sun exposure-dependent differences in 8-hydroxy-2'-deoxyguanosine and N(ε)-(carboxymethyl)lysine in human epidermis
por: Toyokuni, Shinya, et al.
Publicado: (2011)

Lamellar Granule Secretion Starts before the Establishment of Tight Junction Barrier for Paracellular Tracers in Mammalian Epidermis
por: Ishida-Yamamoto, Akemi, et al.
Publicado: (2012)

AGS3 antagonizes LGN to balance oriented cell divisions and cell fate choices in mammalian epidermis
por: Descovich, Carlos P, et al.
Publicado: (2023)

One-pot synthesis of new alkyl 1-naphthoates bearing quinoline, pyranone and cyclohexenone moieties via metal-free sequential addition/oxidation reactions
por: Mousavi, Seyedeh Hekmat, et al.
Publicado: (2021)

Two-dimensional amine and hydroxy functionalized fused aromatic covalent organic framework
por: Mahmood, Javeed, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vgkvnse9r4ra55fm2m4nn0ksjs