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Molecular determinants for Rous sarcoma virus intasome assemblies involved in retroviral integration
Integration of retroviral DNA into the host genome involves the formation of integrase (IN)–DNA complexes termed intasomes. Further characterization of these complexes is needed to understand their assembly process. Here, we report the single-particle cryo-EM structure of the Rous sarcoma virus (RSV...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209032/ https://www.ncbi.nlm.nih.gov/pubmed/37084813 http://dx.doi.org/10.1016/j.jbc.2023.104730 |