Molecular determinants for Rous sarcoma virus intasome assemblies involved in retroviral integration

Integration of retroviral DNA into the host genome involves the formation of integrase (IN)–DNA complexes termed intasomes. Further characterization of these complexes is needed to understand their assembly process. Here, we report the single-particle cryo-EM structure of the Rous sarcoma virus (RSV...

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Detalles Bibliográficos
Autores principales: Bera, Sibes, Shi, Ke, Aihara, Hideki, Grandgenett, Duane P., Pandey, Krishan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209032/
https://www.ncbi.nlm.nih.gov/pubmed/37084813
http://dx.doi.org/10.1016/j.jbc.2023.104730

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