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Hyperphosphorylated PTEN exerts oncogenic properties

PTEN is a multifaceted tumor suppressor that is highly sensitive to alterations in expression or function. The PTEN C-tail domain, which is rich in phosphorylation sites, has been implicated in PTEN stability, localization, catalytic activity, and protein interactions, but its role in tumorigenesis...

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Detalles Bibliográficos
Autores principales:	van Ree, Janine H., Jeganathan, Karthik B., Fierro Velasco, Raul O., Zhang, Cheng, Can, Ismail, Hamada, Masakazu, Li, Hu, Baker, Darren J., van Deursen, Jan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209192/ https://www.ncbi.nlm.nih.gov/pubmed/37225693 http://dx.doi.org/10.1038/s41467-023-38740-x

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