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Evolutionary honing in and mutational replacement: how long-term directed mutational responses to specific environmental pressures are possible

Recent results have shown that the human malaria-resistant hemoglobin S mutation originates de novo more frequently in the gene and in the population where it is of adaptive significance, namely, in the hemoglobin subunit beta gene compared to the nonresistant but otherwise identical 20A[Formula: se...

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Detalles Bibliográficos
Autores principales: Livnat, Adi, Melamed, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209271/
https://www.ncbi.nlm.nih.gov/pubmed/36899155
http://dx.doi.org/10.1007/s12064-023-00387-z

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