Integrated fragmentomic profile and 5-Hydroxymethylcytosine of capture-based low-pass sequencing data enables pan-cancer detection via cfDNA

BACKGROUND: Using epigenetic markers and fragmentomics of cell-free DNA for cancer detection has been proven applicable. METHODS: We further investigated the diagnostic potential of combining two features (epigenetic markers and fragmentomic information) of cell-free DNA for detecting various types...

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Detalles Bibliográficos
Autores principales: Zhang, Zhidong, Pi, Xuenan, Gao, Chang, Zhang, Jun, Xia, Lin, Yan, Xiaoqin, Hu, Xinlei, Yan, Ziyue, Zhang, Shuxin, Wei, Ailin, Guo, Yuer, Liu, Jingfeng, Li, Ang, Liu, Xiaolong, Zhang, Wei, Liu, Yanhui, Xie, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209323/
https://www.ncbi.nlm.nih.gov/pubmed/37209526
http://dx.doi.org/10.1016/j.tranon.2023.101694

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