Cargando…

Advances in lung adenocarcinoma: A novel perspective on prognoses and immune responses of CENPO as an oncogenic superenhancer

Lung adenocarcinoma (LUAD) is the most prevalent form of lung cancer globally, and its treatment remains a significant challenge. Therefore, it is crucial to comprehend the microenvironment to improve therapy and prognosis urgently. In this study, we utilized bioinformatic methods to analyze the tra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Tongdong, Hu, Zaoxiu, Tian, Li, Yang, Yanlong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209335/ https://www.ncbi.nlm.nih.gov/pubmed/37207381 http://dx.doi.org/10.1016/j.tranon.2023.101691

Ejemplares similares

Pan-cancer landscape of CENPO and its underlying mechanism in LUAD
por: Shi, Tongdong, et al.
Publicado: (2023)

Prognostic and immune infiltrative biomarkers of CENPO in pan–cancer and its relationship with lung adenocarcinoma cell proliferation and metastasis
por: Wang, Yuanbiao, et al.
Publicado: (2023)

INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanoma
por: Zhou, Bingying, et al.
Publicado: (2016)

Recurrent Superenhancer of the Oncogene POU5F1B in Colorectal Cancers
por: Tao, Han-chuan, et al.
Publicado: (2021)

Superenhancers: Novel opportunities for nanowire optoelectronics
por: Khudiyev, Tural, et al.
Publicado: (2014)

CENPO is Associated with Immune Cell Infiltration and is a Potential Diagnostic and Prognostic Marker for Hepatocellular Carcinoma
por: He, Kun, et al.
Publicado: (2022)

Superenhancer–transcription factor regulatory network in malignant tumors
por: Liang, Yuan, et al.
Publicado: (2021)

MicroRNA expression profiling of lung adenocarcinoma in Xuanwei, China: A preliminary study
por: Hu, Zaoxiu, et al.
Publicado: (2019)

CENPO expression regulates gastric cancer cell proliferation and is associated with poor patient prognosis
por: Cao, Yi, et al.
Publicado: (2019)

CENPO regulated proliferation and apoptosis of colorectal cancer in a p53-dependent manner
por: Liu, Zhicheng, et al.
Publicado: (2022)

Superenhancers as master gene regulators and novel therapeutic targets in brain tumors
por: Zhuang, Hai-Hui, et al.
Publicado: (2023)

NaviSE: superenhancer navigator integrating epigenomics signal algebra
por: Ascensión, Alex M., et al.
Publicado: (2017)

eRNAs and Superenhancer lncRNAs Are Functional in Human Prostate Cancer
por: Zhang, Xiaona, et al.
Publicado: (2020)

Myeloma-specific superenhancers affect genes of biological and clinical relevance in myeloma
por: Jia, Yunlu, et al.
Publicado: (2021)

CBX7, a Potential Prognostic Biomarker in Lung Adenocarcinoma
por: Yang, Yanlong, et al.
Publicado: (2021)

Superenhancer reprogramming drives a B-cell–epithelial transition and high-risk leukemia
por: Hu, Yeguang, et al.
Publicado: (2016)

Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers
por: Loft, Anne, et al.
Publicado: (2015)

Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling
por: Lee, Derrick, et al.
Publicado: (2023)

Identification of an Autophagy-Related Pair Signature for Predicting Prognoses and Immune Activity in Pancreatic Adenocarcinoma
por: Zhang, Qian, et al.
Publicado: (2021)

The Clinicopathological Characteristics and Prognoses of dMMR Gastric Adenocarcinoma Patients
por: Wang, Jie, et al.
Publicado: (2021)

Immune Gene Signatures and Immunotypes in Immune Microenvironment Are Associated With Glioma Prognose
por: Wang, Xiang-Xu, et al.
Publicado: (2022)

Kras oncogene ablation prevents resistance in advanced lung adenocarcinomas
por: Salmón, Marina, et al.
Publicado: (2023)

A tumor mutational burden-derived immune computational framework selects sensitive immunotherapy/chemotherapy for lung adenocarcinoma populations with different prognoses
por: Zhang, Wenlong, et al.
Publicado: (2023)

Defining the transcriptional control of pediatric AML highlights RARA as a superenhancer-regulated druggable dependency
por: Perez, Monika W., et al.
Publicado: (2021)

Focal amplifications are associated with chromothripsis events and diverse prognoses in gastric cardia adenocarcinoma
por: Zhao, Xue-Ke, et al.
Publicado: (2021)

The prognostic value of cyclooxygenase-2 expression in patients with esophageal cancer: evidence from a meta-analysis
por: Hu, Zaoxiu, et al.
Publicado: (2017)

Characterization of TCF‐1 and its relationship between CD8+ TIL densities and immune checkpoints and their joint influences on prognoses of lung adenocarcinoma patients
por: Jiang, Kanqiu, et al.
Publicado: (2023)

Application of serum microRNA-9-5p, 21-5p, and 223-3p combined with tumor markers in the diagnosis of non-small-cell lung cancer in Yunnan in southwestern China
por: Yang, Yanlong, et al.
Publicado: (2018)

Establishing a Macrophage Phenotypic Switch-Associated Signature-Based Risk Model for Predicting the Prognoses of Lung Adenocarcinoma
por: Chen, Jun, et al.
Publicado: (2022)

Oncogenic RIT1 mutations in lung adenocarcinoma
por: Berger, A H, et al.
Publicado: (2014)

M2-Polarized tumor-associated macrophages are associated with poor prognoses resulting from accelerated lymphangiogenesis in lung adenocarcinoma
por: Zhang, Bicheng, et al.
Publicado: (2011)

The BRD4 Inhibitor dBET57 Exerts Anticancer Effects by Targeting Superenhancer-Related Genes in Neuroblastoma
por: Jia, Si-Qi, et al.
Publicado: (2022)

Superenhancer drives a tumor-specific splicing variant of MARCO to promote triple-negative breast cancer progression
por: Yang, Yun-Song, et al.
Publicado: (2022)

Schlechte Prognose bei Schlaganfall
por: Diener, Hans-Christoph
Publicado: (2020)

Hohes Risiko, schlechte Prognose
por: Diener, Hans-Christoph
Publicado: (2021)

Schlechtere Prognose nach Schlaganfall
por: Diener, Hans-Christoph
Publicado: (2022)

Translocations at 8q24 juxtapose MYC with genes that harbor superenhancers resulting in overexpression and poor prognosis in myeloma patients
por: Walker, B A, et al.
Publicado: (2014)

Immune cell atlas of cholangiocarcinomas reveals distinct tumor microenvironments and associated prognoses
por: Xia, Tao, et al.
Publicado: (2022)

Comparative profiling of immune genes improves the prognoses of lower grade gliomas
por: Wang, Zhiliang, et al.
Publicado: (2022)

Clinical characteristics and prognoses of patients treated surgically for metastatic lung tumors
por: Zhao, Xiaoliang, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_avtvcsq38fft7lgtr8hknk10qd