FFAR4 regulates cardiac oxylipin balance to promote inflammation resolution in HFpEF secondary to metabolic syndrome

Heart failure with preserved ejection fraction (HFpEF) is a complex clinical syndrome, but a predominant subset of HFpEF patients has metabolic syndrome (MetS). Mechanistically, systemic, nonresolving inflammation associated with MetS might drive HFpEF remodeling. Free fatty acid receptor 4 (Ffar4)...

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Detalles Bibliográficos
Autores principales: Zhang, Naixin, Harsch, Brian, Zhang, Michael J., Gyberg, Dylan J., Stevens, Jackie A., Wagner, Brandon M., Mendelson, Jenna, Patterson, Michael T., Orchard, Devin A., Healy, Chastity L., Williams, Jesse W., Townsend, DeWayne, Shearer, Gregory C., Murphy, Katherine A., O'Connell, Timothy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209340/
https://www.ncbi.nlm.nih.gov/pubmed/37075982
http://dx.doi.org/10.1016/j.jlr.2023.100374

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