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A LY6E-PHB1-TRIM21 assembly degrades CD14 protein to mitigate LPS-induced inflammatory response
A major theme of host against invading pathogens lies in multiple regulatory nodes that ensure sufficient signals for protection while avoiding excessive signals toward over-inflammation. The TLR4/MD-2/CD14 complex receptor-mediated response to bacterial lipopolysaccharide (LPS) represents a paradig...
Autores principales: | Zhu, Xinyu, Zhang, Linxia, Feng, Daobin, Jiang, Lang, Sun, Peng, Zhao, Chen, Zhang, Xiaoyan, Xu, Jianqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209397/ https://www.ncbi.nlm.nih.gov/pubmed/37250795 http://dx.doi.org/10.1016/j.isci.2023.106808 |
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