Cargando…

Bioinformatic analyzes and validation of cystathionine gamma-lyase as a prognostic biomarker and related to immune infiltrates in hepatocellular carcinoma

BACKGROUND: The role of cystathionine γ-lyase (CTH) in the prognosis and immune invasion of hepatocellular carcinoma (HCC) remains poorly understood. METHODS: In this study, the clinical data of patients with HCC were analyzed, and the expression level of CTH was compared between HCC and normal tiss...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiang, Jianfeng, Wu, Xinrui, Liu, Wangrui, Wei, Huagen, Zhu, Zhu, Liu, Shifan, Song, Chengqi, Gu, Qiang, Wei, Shiyin, Zhang, Yichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209420/ https://www.ncbi.nlm.nih.gov/pubmed/37251842 http://dx.doi.org/10.1016/j.heliyon.2023.e16152

Ejemplares similares

Cystathionine gamma-lyase (CTH) inhibition attenuates glioblastoma formation
por: Peleli, Maria, et al.
Publicado: (2023)

H(2)S and homocysteine control a novel feedback regulation of cystathionine beta synthase and cystathionine gamma lyase in cardiomyocytes
por: Nandi, Shyam Sundar, et al.
Publicado: (2017)

The expression of cystathionine gamma-lyase is regulated by estrogen receptor alpha in human osteoblasts
por: Lambertini, Elisabetta, et al.
Publicado: (2017)

Cystathionine gamma lyase and hydrogen sulfide: new players in orthodontic root resorption
por: Holliday, L. Shannon, et al.
Publicado: (2020)

A bioinformatic analysis study of m(7)G regulator-mediated methylation modification patterns and tumor microenvironment infiltration in glioblastoma
por: Wu, Xinrui, et al.
Publicado: (2022)

Cystathionine‐gamma‐lyase overexpression in T cells enhances antitumor effect independently of cysteine autonomy
por: Lancien, Melanie, et al.
Publicado: (2021)

Methamphetamine causes cardiovascular dysfunction via cystathionine gamma lyase and hydrogen sulfide depletion
por: Kolluru, Gopi K., et al.
Publicado: (2022)

Heat Shock Protein 70 in Penile Neurovascular Regeneration Requires Cystathionine Gamma-Lyase
por: Ghatak, Kalyan, et al.
Publicado: (2022)

Cystathionine Gamma-Lyase Regulate Psilocybin Biosynthesis in Gymnopilus dilepis Mushroom via Amino Acid Metabolism Pathways
por: Yao, Sen, et al.
Publicado: (2022)

Cystathionine-gamma-lyase inhibitor attenuates acute lung injury induced by acute pancreatitis in rats
por: Qu, Zhen, et al.
Publicado: (2014)

Cystathionine gamma-lyase of perivascular adipose tissue with reversed regulatory effect in diabetic rat artery
por: Emilova, Radoslava, et al.
Publicado: (2015)

Anti-Atherogenic Effect of Hydrogen Sulfide by Over-Expression of Cystathionine Gamma-Lyase (CSE) Gene
por: Cheung, Sau Ha, et al.
Publicado: (2014)

Cystathionine Gamma Lyase Is Regulated by Flow and Controls Smooth Muscle Migration in Human Saphenous Vein
por: Zhao, Shuang, et al.
Publicado: (2023)

Hypoxia increases persulfide and polysulfide formation by AMP kinase dependent cystathionine gamma lyase phosphorylation
por: Alam, Shafiul, et al.
Publicado: (2023)

Expression of Cystathionine β-synthase and Cystathionine γ-lyase in Human Pregnant Myometrium and Their Roles in the Control of Uterine Contractility
por: You, Xing-Ji, et al.
Publicado: (2011)

Integrated machine learning and bioinformatic analyses used to construct a copper-induced cell death-related classifier for prognosis and immunotherapeutic response of hepatocellular carcinoma patients
por: Zhao, Shuai, et al.
Publicado: (2023)

Role of Cystathionine Gamma-Lyase in Immediate Renal Impairment and Inflammatory Response in Acute Ischemic Kidney Injury
por: Markó, Lajos, et al.
Publicado: (2016)

Differential Roles of Cystathionine Gamma-Lyase and Mercaptopyruvate Sulfurtransferase in Hapten-Induced Colitis and Contact Dermatitis in Mice
por: Akahoshi, Noriyuki, et al.
Publicado: (2023)

Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE)
por: Asimakopoulou, Antonia, et al.
Publicado: (2013)

3-Mercaptopyruvate Sulfurtransferase, Not Cystathionine β-Synthase Nor Cystathionine γ-Lyase, Mediates Hypoxia-Induced Migration of Vascular Endothelial Cells
por: Tao, Beibei, et al.
Publicado: (2017)

Caffeic Acid Phenethyl Ester inhibit Hepatic Fibrosis by Nitric Oxide Synthase and Cystathionine Gamma-Lyase in Rats
por: Shi, Yan, et al.
Publicado: (2015)

Enhanced Expression of Cystathionine β-Synthase and Cystathionine γ-Lyase During Acute Cholecystitis-Induced Gallbladder Inflammation
por: Zhang, Li, et al.
Publicado: (2013)

Downregulation of cystathionine β‐synthase and cystathionine γ‐lyase expression stimulates inflammation in kidney ischemia–reperfusion injury
por: Wang, Pengqi, et al.
Publicado: (2014)

Effect of endotoxemia in mice genetically deficient in cystathionine-γ-lyase, cystathionine-β-synthase or 3-mercaptopyruvate sulfurtransferase
por: Ahmad, Akbar, et al.
Publicado: (2016)

Cystathionine-Gamma-Lyase Gene Deletion Protects Mice against Inflammation and Liver Sieve Injury following Polymicrobial Sepsis
por: Gaddam, Ravinder Reddy, et al.
Publicado: (2016)

Cystathionine gamma-lyase (Cth) induces efferocytosis in macrophages via ERK1/2 to modulate intestinal barrier repair
por: Zhao, Xiao-Hu, et al.
Publicado: (2023)

A cardioprotective insight of the cystathionine γ-lyase/hydrogen sulfide pathway
por: Huang, Steve, et al.
Publicado: (2015)

Dysregulation of cystathionine γ‐lyase promotes prostate cancer progression and metastasis
por: Wang, Yi‐Hsiang, et al.
Publicado: (2019)

Cystathionine γ lyase S-sulfhydrates Drp1 to ameliorate heart dysfunction
por: Wu, Dan, et al.
Publicado: (2022)

Cystathionine γ-Lyase Self-Inactivates by Polysulfidation during Cystine Metabolism
por: Araki, Shoma, et al.
Publicado: (2023)

Down-Regulated Expression of Cystathionine β-Synthase and Cystathionine γ-Lyase in Varicocele, and Infertile Men: A Case-Control Study
por: Akbarian, Fahimeh, et al.
Publicado: (2022)

Cystathionine-γ-lyase promotes the metastasis of breast cancer via the VEGF signaling pathway
por: Wang, Lupeng, et al.
Publicado: (2019)

Correction: Cystathionine-Gamma-Lyase Gene Deletion Protects Mice against Inflammation and Liver Sieve Injury following Polymicrobial Sepsis
por: Gaddam, Ravinder Reddy, et al.
Publicado: (2017)

Bioenergetic effects of hydrogen sulfide suppress soluble Flt-1 and soluble endoglin in cystathionine gamma-lyase compromised endothelial cells
por: Sanchez-Aranguren, Lissette Carolina, et al.
Publicado: (2020)

NRF2 Regulates Cystathionine Gamma-Lyase Expression and Activity in Primary Airway Epithelial Cells Infected with Respiratory Syncytial Virus
por: Jamaluddin, Mohammad, et al.
Publicado: (2022)

Cystathionine γ-lyase S-sulfhydrates SIRT1 to attenuate myocardial death in isoprenaline-induced heart failure
por: Wu, Dan, et al.
Publicado: (2023)

Transcriptional regulation of Saccharomyces cerevisiaeCYS3 encoding cystathionine γ-lyase
por: Hiraishi, Hiroyuki, et al.
Publicado: (2008)

Analysis of the sulfur-regulated control of the cystathionine γ-lyase gene of Neurospora crassa
por: Reveal, Brad S, et al.
Publicado: (2012)

Catalytic specificity of the Lactobacillus plantarum cystathionine γ-lyase presumed by the crystallographic analysis
por: Matoba, Yasuyuki, et al.
Publicado: (2020)

Hepatocellular cystathionine γ lyase/hydrogen sulfide attenuates nonalcoholic fatty liver disease by activating farnesoid X receptor
por: Xu, Wenjing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_p2cifreem73eu31423fbuvjt09