APOL1 promotes endothelial cell activation beyond the glomerulus

Apolipoprotein L1 (APOL1) high-risk genotypes are associated with increased risk of chronic kidney disease (CKD) in people of West African ancestry. Given the importance of endothelial cells (ECs) in CKD, we hypothesized that APOL1 high-risk genotypes may contribute to disease via EC-intrinsic activ...

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Detalles Bibliográficos
Autores principales: Carracedo, Miguel, Ericson, Elke, Ågren, Rasmus, Forslöw, Anna, Madeyski-Bengtson, Katja, Svensson, Anna, Riddle, Rebecca, Christoffersson, Jonas, González-King Garibotti, Hernán, Lazovic, Bojana, Hicks, Ryan, Buvall, Lisa, Fornoni, Alessia, Greasley, Peter J., Lal, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209455/
https://www.ncbi.nlm.nih.gov/pubmed/37250770
http://dx.doi.org/10.1016/j.isci.2023.106830

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