Impact of (intestinal) LAL deficiency on lipid metabolism and macrophage infiltration

OBJECTIVE: To date, the only enzyme known to be responsible for the hydrolysis of cholesteryl esters and triacylglycerols in the lysosome at acidic pH is lysosomal acid lipase (LAL). Lipid malabsorption in the small intestine (SI), accompanied by macrophage infiltration, is one of the most common pa...

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Detalles Bibliográficos
Autores principales: Bianco, Valentina, Korbelius, Melanie, Vujic, Nemanja, Akhmetshina, Alena, Amor, Melina, Kolb, Dagmar, Pirchheim, Anita, Bradic, Ivan, Kuentzel, Katharina B., Buerger, Martin, Schauer, Silvia, Phan, Huyen T.T., Bulfon, Dominik, Hoefler, Gerald, Zimmermann, Robert, Kratky, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209539/
https://www.ncbi.nlm.nih.gov/pubmed/37182562
http://dx.doi.org/10.1016/j.molmet.2023.101737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209539/
https://www.ncbi.nlm.nih.gov/pubmed/37182562
http://dx.doi.org/10.1016/j.molmet.2023.101737

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