Pharmacological inhibition of LSD1 suppresses growth of hepatocellular carcinoma by inducing GADD45B

Lysine‐specific histone demethylase 1 (LSD1) is an attractive target for malignancies therapy. Nevertheless, its role in hepatocellular carcinoma (HCC) progression and the potential of its inhibitor in HCC therapy remains unclear. Here, we show that LSD1 overexpression in human HCC tissues is associ...

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Detalles Bibliográficos
Autores principales: Sang, Na, Zhong, Xi, Gou, Kun, Liu, Huan, Xu, Jing, Zhou, Yang, Zhou, Xia, Liu, Yuanzhi, Chen, Zhiqian, Zhou, Yue, Li, Yan, Tao, Lei, Su, Na, Zhou, Lingyun, Qiu, Jiahao, Yang, Xinyu, Zuo, Zeping, Fu, Li, Zhang, Jingyao, Li, Dan, Li, Cong, Sun, Qingxiang, Lei, Jian, Li, Rui, Yang, Shengyong, Cen, Xiaobo, Zhao, Yinglan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209615/
https://www.ncbi.nlm.nih.gov/pubmed/37250145
http://dx.doi.org/10.1002/mco2.269

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