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Isosorbide Mononitrate and Cilostazol Treatment in Patients With Symptomatic Cerebral Small Vessel Disease: The Lacunar Intervention Trial-2 (LACI-2) Randomized Clinical Trial

IMPORTANCE: Cerebral small vessel disease (cSVD) is a common cause of stroke (lacunar stroke), is the most common cause of vascular cognitive impairment, and impairs mobility and mood but has no specific treatment. OBJECTIVE: To test the feasibility, drug tolerability, safety, and effects of 1-year...

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Detalles Bibliográficos
Autores principales: Wardlaw, Joanna M., Woodhouse, Lisa J., Mhlanga, Iris I., Oatey, Katherine, Heye, Anna K., Bamford, John, Cvoro, Vera, Doubal, Fergus N., England, Timothy, Hassan, Ahamad, Montgomery, Alan, O’Brien, John T., Roffe, Christine, Sprigg, Nikola, Werring, David J., Bath, Philip M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209826/
https://www.ncbi.nlm.nih.gov/pubmed/37222252
http://dx.doi.org/10.1001/jamaneurol.2023.1526