Do Physicians Have a Duty to Discuss Expanded Access to Investigational Drugs with their Patients? A Normative Analysis

Drawing on ethical and legal frameworks in the Netherlands, the United States and France, we examine whether physicians are expected to inform patients about potentially relevant opportunities for expanded access to investigational drugs. While we found no definitive legal obligation, we argue that...

Descripción completa

Detalles Bibliográficos
Autores principales: Vermeulen, Stefan F., Hordijk, Marjolijn, Visser, Ruben J., Bunnik, Eline M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Independent Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209970/
https://www.ncbi.nlm.nih.gov/pubmed/37226748
http://dx.doi.org/10.1017/jme.2023.53
Descripción
Sumario:Drawing on ethical and legal frameworks in the Netherlands, the United States and France, we examine whether physicians are expected to inform patients about potentially relevant opportunities for expanded access to investigational drugs. While we found no definitive legal obligation, we argue that physicians have a moral obligation to discuss opportunities for expanded access with patients who have run out of treatment options to prevent inequality, to promote autonomy, and to achieve beneficence.

Ejemplares similares