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Molecular mechanisms of Streptococcus pyogenes Cas9: a single-molecule perspective

Cas9 is an RNA-guided endonuclease from the type II CRISPR-Cas system that employs RNA–DNA base pairing to target and cleave foreign DNA in bacteria. Due to its robust and programmable activity, Cas9 has been repurposed as a revolutionary technology for wide-ranging biological and medical applicatio...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Chen, Ziting, Sun, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biophysics Reports Editorial Office 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210056/
https://www.ncbi.nlm.nih.gov/pubmed/37288365
http://dx.doi.org/10.52601/bpr.2021.210021