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Molecular mechanisms of Streptococcus pyogenes Cas9: a single-molecule perspective
Cas9 is an RNA-guided endonuclease from the type II CRISPR-Cas system that employs RNA–DNA base pairing to target and cleave foreign DNA in bacteria. Due to its robust and programmable activity, Cas9 has been repurposed as a revolutionary technology for wide-ranging biological and medical applicatio...
Autores principales: | Zhang, Qian, Chen, Ziting, Sun, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biophysics Reports Editorial Office
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210056/ https://www.ncbi.nlm.nih.gov/pubmed/37288365 http://dx.doi.org/10.52601/bpr.2021.210021 |
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