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Nanomaterials for the treatment of bacterial infection by photothermal/photodynamic synergism

In the past few decades, great progress has been made in the field of nanomaterials against bacterial infection. However, with the widespread emergence of drug-resistant bacteria, people try their best to explore and develop new antibacterial strategies to fight bacteria without obtaining or increas...

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Autores principales: Yan, Zhaochen, Wang, Danqiu, Gao, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210152/
https://www.ncbi.nlm.nih.gov/pubmed/37251578
http://dx.doi.org/10.3389/fbioe.2023.1192960
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author Yan, Zhaochen
Wang, Danqiu
Gao, Yun
author_facet Yan, Zhaochen
Wang, Danqiu
Gao, Yun
author_sort Yan, Zhaochen
collection PubMed
description In the past few decades, great progress has been made in the field of nanomaterials against bacterial infection. However, with the widespread emergence of drug-resistant bacteria, people try their best to explore and develop new antibacterial strategies to fight bacteria without obtaining or increasing drug resistance. Recently, multi-mode synergistic therapy has been considered as an effective scheme for the treatment of bacterial infections, especially the combination of photothermal therapy (PTT) and photodynamic therapy (PDT) with controllable, non-invasive, small side effects and broad-spectrum antibacterial characteristics. It can not only improve the efficiency of antibiotics, but also do not promote antibiotic resistance. Therefore, multifunctional nanomaterials which combine the advantages of PTT and PDT are more and more used in the treatment of bacterial infections. However, there is still a lack of a comprehensive review of the synergistic effect of PTT and PDT in anti-infection. This review first focuses on the synthesis of synergistic photothermal/photodynamic nanomaterials and discusses the ways and challenges of photothermal/photodynamic synergism, as well as the future research direction of photothermal/photodynamic synergistic antibacterial nanomaterials.
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spelling pubmed-102101522023-05-26 Nanomaterials for the treatment of bacterial infection by photothermal/photodynamic synergism Yan, Zhaochen Wang, Danqiu Gao, Yun Front Bioeng Biotechnol Bioengineering and Biotechnology In the past few decades, great progress has been made in the field of nanomaterials against bacterial infection. However, with the widespread emergence of drug-resistant bacteria, people try their best to explore and develop new antibacterial strategies to fight bacteria without obtaining or increasing drug resistance. Recently, multi-mode synergistic therapy has been considered as an effective scheme for the treatment of bacterial infections, especially the combination of photothermal therapy (PTT) and photodynamic therapy (PDT) with controllable, non-invasive, small side effects and broad-spectrum antibacterial characteristics. It can not only improve the efficiency of antibiotics, but also do not promote antibiotic resistance. Therefore, multifunctional nanomaterials which combine the advantages of PTT and PDT are more and more used in the treatment of bacterial infections. However, there is still a lack of a comprehensive review of the synergistic effect of PTT and PDT in anti-infection. This review first focuses on the synthesis of synergistic photothermal/photodynamic nanomaterials and discusses the ways and challenges of photothermal/photodynamic synergism, as well as the future research direction of photothermal/photodynamic synergistic antibacterial nanomaterials. Frontiers Media S.A. 2023-05-11 /pmc/articles/PMC10210152/ /pubmed/37251578 http://dx.doi.org/10.3389/fbioe.2023.1192960 Text en Copyright © 2023 Yan, Wang and Gao. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Yan, Zhaochen
Wang, Danqiu
Gao, Yun
Nanomaterials for the treatment of bacterial infection by photothermal/photodynamic synergism
title Nanomaterials for the treatment of bacterial infection by photothermal/photodynamic synergism
title_full Nanomaterials for the treatment of bacterial infection by photothermal/photodynamic synergism
title_fullStr Nanomaterials for the treatment of bacterial infection by photothermal/photodynamic synergism
title_full_unstemmed Nanomaterials for the treatment of bacterial infection by photothermal/photodynamic synergism
title_short Nanomaterials for the treatment of bacterial infection by photothermal/photodynamic synergism
title_sort nanomaterials for the treatment of bacterial infection by photothermal/photodynamic synergism
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210152/
https://www.ncbi.nlm.nih.gov/pubmed/37251578
http://dx.doi.org/10.3389/fbioe.2023.1192960
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