Methoxy-naphthyl-Linked N-Benzyl Pyridinium Styryls as Dual Cholinesterase Inhibitors: Design, Synthesis, Biological Evaluation, and Structure–Activity Relationship

[Image: see text] The multifaceted nature of Alzheimer’s disease (AD) indicates the need for multitargeted agents as potential therapeutics. Both cholinesterases (ChEs), acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), play a vital role in disease progression. Thus, inhibiting both ChEs...

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Detalles Bibliográficos
Autores principales: Abdullaha, Mohd, Banoo, Razia, Nuthakki, Vijay K., Sharma, Mohit, Kaur, Sukhleen, Thakur, Shikha, Kumar, Ajay, Jadhav, Hemant R., Bharate, Sandip B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210183/
https://www.ncbi.nlm.nih.gov/pubmed/37251153
http://dx.doi.org/10.1021/acsomega.2c08167

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