Cargando…

Segmentation and Morphology Computation of a Spiky Nanoparticle Using the Hourglass Neural Network

[Image: see text] Morphological measurements of nanoparticles in electron microscopy images are tedious, laborious, and often succumb to human errors. Deep learning methods in artificial intelligence (AI) paved the way for automated image understanding. This work proposes a deep neural network (DNN)...

Descripción completa

Detalles Bibliográficos
Autores principales: Hussain, Muhammad Ishfaq, Rafique, Muhammad Aasim, Jung, Wan-Gil, Kim, Bong-Joong, Jeon, Moongu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210197/
https://www.ncbi.nlm.nih.gov/pubmed/37251121
http://dx.doi.org/10.1021/acsomega.3c00783
Descripción
Sumario:[Image: see text] Morphological measurements of nanoparticles in electron microscopy images are tedious, laborious, and often succumb to human errors. Deep learning methods in artificial intelligence (AI) paved the way for automated image understanding. This work proposes a deep neural network (DNN) for the automated segmentation of a Au spiky nanoparticle (SNP) in electron microscopic images, and the network is trained with a spike-focused loss function. The segmented images are used for the growth measurement of the Au SNP. The auxiliary loss function captures the spikes of the nanoparticle, which prioritizes the detection of spikes in the border regions. The growth of the particles measured by the proposed DNN is as good as the measurement in manually segmented images of the particles. The proposed DNN composition with the training methodology meticulously segments the particle and consequently provides accurate morphological analysis. Furthermore, the proposed network is tested on an embedded system for integration with the microscope hardware for real-time morphological analysis.