Convenient Synthesis of Salicylanilide Sulfonates from 1,2,3-Benzotriazin-4(3H)-ones and Organosulfonic Acids via Denitrogenative Cross-Coupling

[Image: see text] An efficient and straightforward approach to synthesize salicylanilide aryl and alkyl sulfonates from 1,2,3-benzotriazin-4(3H)-ones and organosulfonic acids is described. This protocol is operationally simple and scalable, exhibits a broad substrate scope with high functional group...

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Autores principales: Korivi, Ramaraju, Madasamy, Kanagaraj, Sureshbabu, Popuri, Mannathan, Subramaniyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210227/
https://www.ncbi.nlm.nih.gov/pubmed/37251178
http://dx.doi.org/10.1021/acsomega.3c02165
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author Korivi, Ramaraju
Madasamy, Kanagaraj
Sureshbabu, Popuri
Mannathan, Subramaniyan
author_facet Korivi, Ramaraju
Madasamy, Kanagaraj
Sureshbabu, Popuri
Mannathan, Subramaniyan
author_sort Korivi, Ramaraju
collection PubMed
description [Image: see text] An efficient and straightforward approach to synthesize salicylanilide aryl and alkyl sulfonates from 1,2,3-benzotriazin-4(3H)-ones and organosulfonic acids is described. This protocol is operationally simple and scalable, exhibits a broad substrate scope with high functional group tolerance, and affords the desired products in good to high yield. Application of the reaction is also demonstrated by converting the desired product to synthetically useful salicylamides in high yields.
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spelling pubmed-102102272023-05-26 Convenient Synthesis of Salicylanilide Sulfonates from 1,2,3-Benzotriazin-4(3H)-ones and Organosulfonic Acids via Denitrogenative Cross-Coupling Korivi, Ramaraju Madasamy, Kanagaraj Sureshbabu, Popuri Mannathan, Subramaniyan ACS Omega [Image: see text] An efficient and straightforward approach to synthesize salicylanilide aryl and alkyl sulfonates from 1,2,3-benzotriazin-4(3H)-ones and organosulfonic acids is described. This protocol is operationally simple and scalable, exhibits a broad substrate scope with high functional group tolerance, and affords the desired products in good to high yield. Application of the reaction is also demonstrated by converting the desired product to synthetically useful salicylamides in high yields. American Chemical Society 2023-05-09 /pmc/articles/PMC10210227/ /pubmed/37251178 http://dx.doi.org/10.1021/acsomega.3c02165 Text en © 2023 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Korivi, Ramaraju
Madasamy, Kanagaraj
Sureshbabu, Popuri
Mannathan, Subramaniyan
Convenient Synthesis of Salicylanilide Sulfonates from 1,2,3-Benzotriazin-4(3H)-ones and Organosulfonic Acids via Denitrogenative Cross-Coupling
title Convenient Synthesis of Salicylanilide Sulfonates from 1,2,3-Benzotriazin-4(3H)-ones and Organosulfonic Acids via Denitrogenative Cross-Coupling
title_full Convenient Synthesis of Salicylanilide Sulfonates from 1,2,3-Benzotriazin-4(3H)-ones and Organosulfonic Acids via Denitrogenative Cross-Coupling
title_fullStr Convenient Synthesis of Salicylanilide Sulfonates from 1,2,3-Benzotriazin-4(3H)-ones and Organosulfonic Acids via Denitrogenative Cross-Coupling
title_full_unstemmed Convenient Synthesis of Salicylanilide Sulfonates from 1,2,3-Benzotriazin-4(3H)-ones and Organosulfonic Acids via Denitrogenative Cross-Coupling
title_short Convenient Synthesis of Salicylanilide Sulfonates from 1,2,3-Benzotriazin-4(3H)-ones and Organosulfonic Acids via Denitrogenative Cross-Coupling
title_sort convenient synthesis of salicylanilide sulfonates from 1,2,3-benzotriazin-4(3h)-ones and organosulfonic acids via denitrogenative cross-coupling
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210227/
https://www.ncbi.nlm.nih.gov/pubmed/37251178
http://dx.doi.org/10.1021/acsomega.3c02165
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