Neuroprotective effects of the PPARβ/δ antagonist GSK0660 in in vitro and in vivo Parkinson’s disease models

BACKGROUND: The underlying mechanism of Parkinson’s disease are still unidentified, but excitotoxicity, oxidative stress, and neuroinflammation are considered key actors. Proliferator activated receptors (PPARs) are transcription factors involved in the control of numerous pathways. Specifically, PP...

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Detalles Bibliográficos
Autores principales: Antonosante, Andrea, Castelli, Vanessa, Sette, Martina, Alfonsetti, Margherita, Catanesi, Mariano, Benedetti, Elisabetta, Ardini, Matteo, Cimini, Annamaria, d’Angelo, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210307/
https://www.ncbi.nlm.nih.gov/pubmed/37226204
http://dx.doi.org/10.1186/s40659-023-00438-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210307/
https://www.ncbi.nlm.nih.gov/pubmed/37226204
http://dx.doi.org/10.1186/s40659-023-00438-1

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