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Neuroprotective effects of the PPARβ/δ antagonist GSK0660 in in vitro and in vivo Parkinson’s disease models
BACKGROUND: The underlying mechanism of Parkinson’s disease are still unidentified, but excitotoxicity, oxidative stress, and neuroinflammation are considered key actors. Proliferator activated receptors (PPARs) are transcription factors involved in the control of numerous pathways. Specifically, PP...
Autores principales: | Antonosante, Andrea, Castelli, Vanessa, Sette, Martina, Alfonsetti, Margherita, Catanesi, Mariano, Benedetti, Elisabetta, Ardini, Matteo, Cimini, Annamaria, d’Angelo, Michele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210307/ https://www.ncbi.nlm.nih.gov/pubmed/37226204 http://dx.doi.org/10.1186/s40659-023-00438-1 |
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