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Hyperglycemia and O-GlcNAc transferase activity drive a cancer stem cell pathway in triple-negative breast cancer

BACKGROUND: Enhanced glucose metabolism is a feature of most tumors, but downstream functional effects of aberrant glucose flux are difficult to mechanistically determine. Metabolic diseases including obesity and diabetes have a hyperglycemia component and are correlated with elevated pre-menopausal...

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Detalles Bibliográficos
Autores principales: Ayodeji, Saheed A., Bao, Bin, Teslow, Emily A., Polin, Lisa A., Dyson, Greg, Bollig-Fischer, Aliccia, Fehl, Charlie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210312/
https://www.ncbi.nlm.nih.gov/pubmed/37231419
http://dx.doi.org/10.1186/s12935-023-02942-6

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