A bispecific antibody AP203 targeting PD-L1 and CD137 exerts potent antitumor activity without toxicity

BACKGROUND: Bispecific antibody has garnered considerable attention in the recent years due to its impressive preliminary efficacy in hematological malignancies. For solid tumors, however, the main hindrance is the suppressive tumor microenvironment, which effectively impedes the activation of infil...

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Detalles Bibliográficos
Autores principales: Huang, Po-Lin, Kan, Hung-Tsai, Hsu, Ching-Hsuan, Hsieh, Hsin-Ta, Cheng, Wan-Chien, Huang, Ren-Yeong, You, Jhong-Jhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210478/
https://www.ncbi.nlm.nih.gov/pubmed/37226226
http://dx.doi.org/10.1186/s12967-023-04193-5

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